A Case of Deep Vein thrombosis due to Protein C, Protein S Deficiency and Hyper-Homocystinaemia, A Rare Genetic Abnormalities

Authors

  • Ahmed Hossain Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka
  • Quazi Tarikul Islam Professor (PRL), Department of Medicine, Dhaka Medical College, Dhaka
  • Umme Kulsum Mitu Post graduate Trainee, Dept. of Medicine, Dhaka Medical College Hospital, Dhaka
  • Jayanta Banik Post graduate Trainee, Dept. of Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • HM Mostafisur Rahman Assistant Registrar, ,Dept. of Medicine, Dhaka Medical College Hospital, Dhaka
  • Mahmud Hasan Internal Medical Officer, Dept. of Medicine, Dhaka Medical College Hospital, Dhaka
  • ABM Golam Mostafa Internal Medical Officer, Dept. of Medicine, Dhaka Medical College Hospital, Dhaka

DOI:

https://doi.org/10.3329/bjmed.v22i1.13598

Keywords:

Deep Vein Thromboses, protein C, protein S, thrombophilia, hyperhomocystinaemia

Abstract

Approximately 80% of Deep Vein Thromboses (DVTs) are clinically asymptomatic, 20% of those that actually demonstrate signs and symptoms. DVT associated with protein C and protein S deficiencies are rare genetic abnormalities that cause thrombophilia and lead to thrombosis. Here we describe a case of 55-year old male who presented with recurrent DVT of left lower limb and eventually diagnosed as a case of DVT due to protein C and protein S deficiency with hyperhomocystinaemia.. The particular interest in this case report is that it is important to consider sceening for thrombophilia incase of DVT with uncertain aetiology.

DOI: http://dx.doi.org/10.3329/bjmed.v22i1.13598

Bangladesh J Medicine 2011; 22: 27-29

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Published

2013-02-02

How to Cite

Hossain, A., Islam, Q. T., Mitu, U. K., Banik, J., Rahman, H. M., Hasan, M., & Mostafa, A. G. (2013). A Case of Deep Vein thrombosis due to Protein C, Protein S Deficiency and Hyper-Homocystinaemia, A Rare Genetic Abnormalities. Bangladesh Journal of Medicine, 22(1), 27–29. https://doi.org/10.3329/bjmed.v22i1.13598

Issue

Vol. 22 No. 1 (2011)

Section

Case Reports