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Post a Comment A comparative study on the effect of streptokinase between diabetic and non-diabetic myocardial infarction patients
Abstract
A prospective interventional study was carried out to compare the thrombolytic effect of streptokinase between diabetic and non-diabetic myocardial infarction patients. Out of 187 study subjects with acute ST segment elevation myocardial infarction (STEMI), admitted at coronary care unit, 126 patients were non-diabetic and 61 patients were diabetic. Streptokinase was administered to all patients. Resolution (reduction) of elevated ST segment was evaluated after 90 minutes of streptokinase administration. Successful reperfusion (≤70% ST-resolution) was significantly higher in non-diabetic than diabetic (p<0.001), while failed reperfusion (<30% ST resolution) was significantly higher in diabetic patients (p<0.001). It may be concluded that diabetes mellitus might affect the thrombolytic outcome of acute myocardial infarction patients with diabetes mellitus.
Keywords: diabetes mellitus; myocardial infarction; streptokinase
Online 11 Apr 2008
DOI: 10.3329/bjp.v3i1.822
Bangladesh J Pharmacol 2007; 3: 1-7.
Keywords
This work is licensed under a Creative Commons Attribution 3.0 License.
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