Antibiotic sensitivity pattern of urinary tract infection at a tertiary care hospital

Authors

  • Rama Biswas Specialist, Medicine, Square Hospital Ltd, Dhaka
  • Raihan Rabbani Associate Consultant, Square Hospital Ltd, Dhaka
  • Hasan Shahrear Ahmed Medical Officer, Surgery, BSMMU
  • Mohammed Abdus Satter Sarker Assistant Professor, SSMC and Mitford Hospital, Dhaka
  • Nahida Zafrin Medical Officer, Pathology, Sylhet Medical College, Sylhet
  • Md Motlabur Rahman Assistant Professor, DMC

DOI:

https://doi.org/10.3329/bccj.v2i1.19952

Keywords:

Urinary Tract Infection, Antibiotic Sensitivity

Abstract

Background: Urinary tract infections (UTIs) remain the common infections in outpatients as well as hospitalized patients. Current knowledge on antimicrobial sensitivity pattern is essential for appropriate therapy. The aim of the study is to determine the changing pattern of antibiotic sensitivity among uropathogens causing UTI.

Methods: Urinary isolates from symptomatic UTI cases attending in Square hospital were processed in the Microbiology lab. Antimicrobial susceptibility testing was performed by Kirby Bauers disc diffusion method. Extended spectrum beta lactamase (ESBL) production was determined by double disk synergy test method.

Results: Of the 200 tested sample 110 samples showed growth of pathogens among which the most prevalent were E.coli (58.18%) followed by Enterococci (13.6%). The majority (68.18%) of the isolates were from female. ESBL production was observed in 46.87% o E.coli strains and 25% of Klebsiella strains. More than 98% of the isolates are sensitive to Imipenem, Meropenem , while 86.36% are sensitive to Amikacin, 73.63% to Nitrofurantoin and 74.54% to Gentamicin. Very high rate of resistance is seen against amoxicillin (88.19%), cefixime (65.46%), cotrimoxazole (68.19%) and ceftriaxone (63.63%). E. coli showed high sensitivity to meropenem, imipenem and amikacin (100%) followed by Gentamicin (94.1%).

Conclusion: The study revealed that E.coli was the predominant bacterial pathogens of UTIs. An increasing trend in the production ESBLs among UTI pathogens in the community was noted. Nitrofurantoin should be used as empirical therapy for primary, uncomplicated UTIs.

DOI: http://dx.doi.org/10.3329/bccj.v2i1.19952

Bangladesh Crit Care J March 2014; 2 (1): 21-24

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Published

2014-08-11

How to Cite

Biswas, R., Rabbani, R., Ahmed, H. S., Sarker, M. A. S., Zafrin, N., & Rahman, M. M. (2014). Antibiotic sensitivity pattern of urinary tract infection at a tertiary care hospital. Bangladesh Critical Care Journal, 2(1), 21–24. https://doi.org/10.3329/bccj.v2i1.19952

Issue

Vol. 2 No. 1 (2014)

Section

Original Articles

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