Euglycemic Diabetic Ketoacidosis Presenting as Chest Pain and Vomiting in a Patient taking SGLT-2 inhibitor

Authors

  • Imrana Ali Phase B Resident (Critical Care Medicine), Department of Anesthesia, Pain, Palliative & Intensive Care, Dhaka Medical College Hospital
  • Saifullah Al Kafi Phase B Resident (Critical Care Medicine), Department of Anesthesia, Pain, Palliative & Intensive Care, Dhaka Medical College Hospital
  • A K M Ferdous Rahman Associate Professor, Department of Critical Care Medicine, Dhaka Medical College Hospital
  • Mohammad Salim Associate Professor, Department of Critical Care Medicine, Dhaka Medical College Hospital
  • Sardar Mohammad Tanvir Assistant Professor, Department of Critical Care Medicine, Dhaka Medical College Hospital
  • Md Habibullah Assistant Professor, Department of Critical Care Medicine, Dhaka Medical College Hospital

DOI:

https://doi.org/10.3329/bccj.v12i2.76432

Keywords:

Euglycemic Diabetic Ketoacidosis, Diabetes Mellitus, SGLT-2 inhibitors, Empagliflozin

Abstract

Empagliflozin-induced Euglycemic Diabetic Ketoacidosis (EDKA) is a life-threatening metabolic emergency of Diabetes Mellitus. It is characterized by metabolic acidosis (i.e., pH <7.3 and Serum bicarbonate <15mEq/dl) with an increased anion gap, ketonemia and relatively normal serum glucose level. EDKA resembles Diabetic Keto Acidosis (DKA) but does not exhibit the typical high blood sugar levels. In EDKA, blood glucose is usually below 200 mg/dL. This condition is a diagnostic challenge as euglycemia masks the underlying diabetic ketoacidosis. Here we present a case of Empagliflozin-induced Euglycemic Diabetic Ketoacidosis presented with palpitation and several episodes of vomiting. The aim of this article is to create awareness among clinicians to consider this diagnosis in the differential, especially in the patients taking SGLT-2 inhibitors.

Bangladesh Crit Care J September 2024; 12 (2): 172-174

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Published

2024-10-16

How to Cite

Ali, I., Kafi, S. A., Rahman, A. K. M. F., Salim, M., Tanvir, S. M., & Habibullah, M. (2024). Euglycemic Diabetic Ketoacidosis Presenting as Chest Pain and Vomiting in a Patient taking SGLT-2 inhibitor. Bangladesh Critical Care Journal, 12(2), 172–174. https://doi.org/10.3329/bccj.v12i2.76432

Issue

Vol. 12 No. 2 (2024)

Section

Case Reports

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