Hepatitis B and Hepatitis C Virus Infection among End Stage Renal Disease Patients on Maintenance Hemodialysis, Their Family Members and Dialysis Staffs - A Prevalence Study

Authors

  • Rana Mokarram Hossain Associate Professor, Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • M Masud Iqbal Associate Professor, Department of Nephrology, Sir Salimullah Medical College (SSMC), Dhaka
  • Zeenat Farzana Rahman Senior Research Officer, Department of Immunology, Bangladesh Institute of Research and Rehabilitation in Endocrine and Metabolic Disorders (BIRDEM) Hospital, Dhaka
  • Rosy Sultana Associate Professor, Department of Immunology, Bangladesh University of Health Sciences (BUHS), Dhaka
  • Md Habibur Rahman Ex-Professor, Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • Md Nazrul Islam Ex-Professor, Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • Nazmun Nahar Khan Research Assistant, Department of Immunology, BIRDEM Hospital, Dhaka
  • Md Abul Mansur Professor, Department of Nephrology, BIRDEM Hospital, Dhaka
  • Md Anisur Rahman Associate Professor, Department of Nephrology, BIRDEM Hospital, Dhaka
  • Sarwar Iqbal Professor, Department of Nephrology, BIRDEM Hospital, Dhaka
  • M Sawkat Hassan Professor, Department of Laboratory Services, Ali Asgor Hospital, Dhaka

DOI:

https://doi.org/10.3329/birdem.v8i1.35038

Keywords:

Hepatitis B virus, Hepataitis C Virus, Infection, first degree relative, hospital staff

Abstract

Background: Hepatitis B (HBV) and hepatitis C virus (HCV) infection is common among patients on maintenance hemodialysis (MHD). This study was undertaken to observe prevalence of hepatitis B and C infection in hemodialysis patients, their family members and dialysis staffs.

Methods: In this cross-sectional study 3 groups were included as gr-1 patients on MHD, the first-degree relatives in gr-2 and the dialysis staffs as gr-3. Clinical and laboratory investigations were done. Viral serology included hepatitis B surface antigen (HBsAg) and antibody against hepatitis C virus (anti-HCV) done by enzyme linked immunosorbent sorbent assay (ELISA) method.

Results: Total 150 subjects were analyzed where 50 were in gr-1, 60 gr-2 and 40 in gr-3. In gr-1 MHD patients, HBV infection was positive in 12% and HCV in 71%. None of the viral markers were positive in family members and dialysis staffs. Blood transfusion (BT) was taken by 76% MHD patents. The frequency of HBV and HCV infection was of similar pattern in both BT dependent and non BT group (P=NS).When HCV positive and negative patents were (71 vs. 29%, p<0.001) compared, dialysis duration (37 ± 34 vs. 11± 6 months, p<0.001) was found higher in positive patients.

Conclusion: This survey on dialysis patients showed that prevalence of hepatitis B and C virus infections was higher in Bangladeshi patients on MHD groups. Horizontal spread of these viruses is negligible in caregivers and dialysis staffs.

Birdem Med J 2018; 8(1): 42-46

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Published

2017-12-27

How to Cite

Hossain, R. M., Iqbal, M. M., Rahman, Z. F., Sultana, R., Rahman, M. H., Islam, M. N., Khan, N. N., Mansur, M. A., Rahman, M. A., Iqbal, S., & Hassan, M. S. (2017). Hepatitis B and Hepatitis C Virus Infection among End Stage Renal Disease Patients on Maintenance Hemodialysis, Their Family Members and Dialysis Staffs - A Prevalence Study. BIRDEM Medical Journal, 8(1), 42–46. https://doi.org/10.3329/birdem.v8i1.35038

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Original Articles