Time-dependent variations in urine volume and serum creatinine levels during post-operative hospital stay period after renal transplantation: experience in a tertiary care hospital of Bangladesh

Authors

  • Mohammad Mehfuz E Khoda Junior Consultant, Kidney Transplant Unit, BADAS & Nephrology and Dialysis Unit, BIRDEM General Hospital, Dhaka, Bangladesh
  • Muhammad Abdur Rahim Associate Professor, Department of Nephrology, BIRDEM General Hospital, Dhaka, Bangladesh
  • Ishrat Jahan Shimu Assistant Professor, Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Md Golzar Hossain Transplant Coordinator, Kidney Transplant Unit, BADAS & Senior Medical Officer, Nephrology and Dialysis Unit, BIRDEM General Hospital, Dhaka, Bangladesh
  • Ahmed Sharif Senior Medical Officer, Nephrology and Dialysis Unit, BIRDEM General Hospital, Dhaka, Bangladesh
  • Md Abul Mansur Director, Kidney Transplant Unit, BADAS & Professor, Nephrology and Dialysis Unit, BIRDEM General Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/birdem.v10i3.48702

Keywords:

kidney transplant recipient, urine volume, serum creatinine

Abstract

Background: Kidney transplantation is the preferred treatment for end stage kidney disease (ESKD). Early post kidney transplant urine volume may correlate with favorable allograft survival. The aim of the present study was to examine the potential changes in urine volume with serum creatinine during post-operative hospital stay period after renal transplantation.

Methods: We retrospectively reviewed the medical records of patients who had undergone kidney transplantation at Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, Bangladesh between November 2004 and February 2019. Total patients were 133. Twenty four hour urine volume and serum creatinine levels were measured on day 1, day 5 and day 10 after operation. Correlation was performed by using Pearson correlation test.

Results: The mean age of the renal allograft recipients was 36.7±10.3 years with male to female ratio of 2.7:1. The mean 24 hours urine volume on Day 1, Day 5 and Day 10 were 8990±5377 ml, 4860±2074 ml and 4485±1722 ml respectively and serum creatinine levels were 3.5±1.5 mg/dl, 1.6±1.2 mg/dl and 1.5±1.3 mg/dl respectively. Negative correlation were found between the Day 1, Day 5 and Day 10 serum creatinine and the urine volume (r=0.366, 0.507, 0.365 respectively) with significant p values (<0.01) in each group.

Conclusion: Although urine volume showed considerable variation in early post renal transplantation, it stabilized by the course of time, which was also negatively correlated with the serum creatinine levels.

Birdem Med J 2020; 10(3): 149-151

Downloads

Download data is not yet available.
Abstract
164
PDF
212

Downloads

Published

2020-08-23

How to Cite

Khoda, M. M. E., Rahim, M. A., Shimu, I. J., Hossain, M. G., Sharif, A., & Mansur, M. A. (2020). Time-dependent variations in urine volume and serum creatinine levels during post-operative hospital stay period after renal transplantation: experience in a tertiary care hospital of Bangladesh. BIRDEM Medical Journal, 10(3), 149–151. https://doi.org/10.3329/birdem.v10i3.48702

Issue

Section

Original Articles