Precocious puberty: diagnosis and management

Authors

  • Nusrat Sultana Assistant Professor, Department of Endocrinology, BSMMU, Bangladesh
  • Faria Afsana Assistant Professor, Department of Endocrinology, BIRDEM, Bangladesh
  • Nazma Akhtar Assistant Professor, Department of Endocrinology, Shaheed Tazuddin Ahmed Medical College, Bangladesh
  • Yasmin Aktar Assistant Professor, Department of Endocrinology, Bangladesh Medical College and Hospital, Bangladesh
  • Mohammad Feroz Amin Associate Professor, Department of Endocrinology, BIRDEM, Bangladesh
  • Sharmin Chowdhury Medical Officer, National Institute of Neurosciences and Hospital, Bangladesh
  • Shah Md Emran Associate Professor, Department of Endocrinology, Sylhet M.A.G Osmani Medical College and Hospital, Bangladesh
  • ABM Kamrul Hasan Assistant Prof and Head, Department of Endocrinology, Mymensingh Medical College and Hospital, Bangladesh
  • Tanjina Hossain Associate Professor, Department of Endocrinology and Metabolism, Green Life Medical college and Hospital, Bangladesh
  • Murshed Ahmed Khan Assistant Professor, Department of Endocrinology, BSMMU, Bangladesh
  • Shahjamal Khan Professor & Head, Department of Endocrinology, Enam Medical College and Hospital, Bangladesh
  • Mohammad Imtiaj Mahbub Assistant Professor, Sheikh Hasina National Institute of Burn and plastic Surgery, Bangladesh
  • Ahmed Salam Mir Associate Professor, Department of Endocrinology, BIHS, Bangladesh
  • Marufa Mustari Endocrinologist, Department of Endocrinology, BSMMU, Bangladesh
  • - Md Rafiquddin Assistant Professor, Department of Endocrinology, Chittagong Medical college and Hospital, Bangladesh
  • Md Atikur Rahman Junior Consultant (in situ) Surgeon Office, Munshiganj, Bangladesh
  • Sultana Marufa Shefin Assistant Professor, Department of Endocrinology, BIRDEM, Bangladesh
  • Dahlia Sultana Assistant Professor, Department of Endocrinology, SSMC &MH, Bangladesh
  • Samir Kumar Talukder Associate Professor and Head, Department of Endocrinology, Rangpur Medical College and Hospital, Bangladesh
  • Sadiqa Tuqan Associate Consultant, Square Hospital Ltd, Bangladesh

DOI:

https://doi.org/10.3329/birdem.v12i1.57228

Keywords:

Precocious puberty, central precocious puberty, peripheral precocious puberty, pubertal variants

Abstract

Precocious puberty is commonly defined as puberty that starts before age 8 years in girls and 9 years in boys. The causes of it may range from a variant of normal development to various pathologic conditions. The etiology of precocious puberty is classified by the underlying pathogenesis into gonadotropin dependent central precocious puberty and peripheral precocious puberty which is independent of gonadotropin but due to different other causes. Variants of precocious puberty include premature thelarche, premature puberche and isolated premature menarche which imply onset of isolated changes without any other signs of sexual development. Precocious puberty might have an impact on final stature owing to premature epiphyseal fusion and also it has got influence on psychosocial wellbeing. Evaluation includes a detailed history, physical examination, biochemical testing and imaging directed towards suspected etiology. Gonadotropin releasing hormone (GnRH) analogues are effective for treatment of central precocious puberty. Treatment of peripheral precocious puberty should be based on the specific cause. Pubertal variants are usually non-progressive and need no treatment but should be monitored carefully.

BIRDEM Med J 2022; 12(1): 62-69

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Published

2021-12-30

How to Cite

Sultana, N. ., Afsana, F. ., Akhtar, N. ., Aktar, Y. ., Amin, M. F. ., Chowdhury, S. ., Md Emran, S. ., Hasan, A. K. ., Hossain, T. ., Khan, M. A. ., Khan, S. ., Mahbub, M. I. ., Salam Mir, A. ., Mustari, M. ., Md Rafiquddin, .-., Rahman, M. A. ., Shefin, S. M. ., Sultana, D. ., Talukder, S. K. ., & Tuqan, S. . (2021). Precocious puberty: diagnosis and management. BIRDEM Medical Journal, 12(1), 62–69. https://doi.org/10.3329/birdem.v12i1.57228

Issue

Section

Review Articles