Isolation of Multidrug Resistant Bacteria from Aspirates of Cancer Patients

Authors

  • Sunjukta Ahsan Department of Microbiology, University of Dhaka, Dhaka-1000
  • Rayhan Mahmud Department of Microbiology, Jagannath University, Dhaka
  • Kajal Ahsan Department of Cytopathology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka 1212
  • Shamima Begum Department of Microbiology, Jagannath University, Dhaka

DOI:

https://doi.org/10.3329/bjm.v35i1.39805

Keywords:

Isolation, Multidrug Resistant, Cancer Patients

Abstract

Infections due to Gram-negative bacteria are common affairs in cancer patients during aggressive therapy. The present study characterizedmulti-drug resistant bacteria (MDR) isolated from cancer aspirates collected from patients admitted to the National Cancer Hospital in Dhaka, Bangladesh. A total of 210 aspirate samples were collected from cancer patients. Out of 210 samples Acinetobacter spp.led the list of isolates (8.89%, n=45). Of these species, 50% exhibited resistance to Amoxycillin and Nitrofurantoin, each, 25% exhibited resistant to Cefotaxime, Azithromycin, Ciprofloxacin, Clindamycin, and Sulfamethoxazole. A total of 33.33% of the Bordetella spp.which accounted 6.67%of the total isolates exhibited resistance to Cefotaxime. All oftheLegionellapneumophila,comprising 4.4%of the isolated species, wereresistant to Cefotaxime, Azithromycin, and Clindamycin.In contrast, 50% were resistant to Cefotaxime, Azithromycin, and Ceftriaxone. Of the Escherichia coli(4.4%, n=45) isolated,50% exhibited resistance to Cefotaxime, Clindamycin, Ceftriaxone, Amoxycillinand Sulfamethoxazole.The only isolate of Klebsiella sp. was demonstrated to be an ESBL producer. The isolation of multidrug resistant bacteria from cancer patients is of particular concern in Bangladesh where cancer and drug resistance are both common phenomena but treatment facilities are poor. To our knowledge this is the first report of the isolation of drug resistant bacteria from cancer patients from Dhaka city.

Bangladesh J Microbiol, Volume 35 Number 1 June 2018, pp 61-66

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Author Biographies

Sunjukta Ahsan, Department of Microbiology, University of Dhaka, Dhaka-1000

Department of Microbiology

Rayhan Mahmud, Department of Microbiology, Jagannath University, Dhaka

Department of Microbiology

Kajal Ahsan, Department of Cytopathology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka 1212

Department of Cytopathology

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Published

2019-01-15

How to Cite

Ahsan, S., Mahmud, R., Ahsan, K., & Begum, S. (2019). Isolation of Multidrug Resistant Bacteria from Aspirates of Cancer Patients. Bangladesh Journal of Microbiology, 35(1), 61–66. https://doi.org/10.3329/bjm.v35i1.39805

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Articles