Nucleoids Dynamic in Escherichia coli: A Growth Phase Dependent Process

Authors

  • Ali Azam Talukder Department of Microbiology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh
  • M Anwar Hossain Department of Microbiology, University of Dhaka, Dhaka 1000, Bangladesh
  • Mamoru Yamada Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi 753-8515, Japan
  • Akira Ishihama National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan

DOI:

https://doi.org/10.3329/bjm.v23i2.867

Keywords:

Escherichia coli, Nucleoid body, Nucleoid proteins, Nucleoid compaction, Condensin

Abstract

Bacterial DNA compacts in nucleoid bodies. The organization of nucleoid body depends on the association of genomic DNA with a numbers of histone-like proteins. The relax nucleoids organization in rapidly growing Escherichia coli cells associate with six major proteins, Fis, HU, Hfq, H-NS, StpA and IHF, but at stationary phase the nucleoids further tightly pack with Dps. The final steps of compact nucleoids formation occurs with association of MukBEF complex - a bacterial condensin. The change of nucleoid proteins composition in stationary phase accompanies compact DNA organization and genes silencing. Thus, compact nucleoid organization and gene silencing may be crucial for cell survival in stationary phase.

Keywords: Escherichia coli, Nucleoid body, Nucleoid proteins, Nucleoid compaction, Condensin

DOI: http://dx.doi.org/10.3329/bjm.v23i2.867

Bangladesh J Microbiol, Volume 23, Number 2, December 2006, pp 81-88

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How to Cite

Talukder, A. A., Hossain, M. A., Yamada, M., & Ishihama, A. (2008). Nucleoids Dynamic in Escherichia coli: A Growth Phase Dependent Process. Bangladesh Journal of Microbiology, 23(2), 81–88. https://doi.org/10.3329/bjm.v23i2.867

Issue

Vol. 23 No. 2 (2006)

Section

Articles