Comparable Efficacy of Terbinafine and Itraconazole in the Treatment of Tinea Pedis

Authors

  • Md Abdul Wahab Associate Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka,
  • Mohammad Jamal Uddin Assistant Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Biswas Shahen Hassan MD (Dermatology) Student, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Zafrul Islam Medical officer, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Ishrat Bhuiyan Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Mohammad Rahmat Ullah Siddique Research Assistant, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/bjmed.v21i2.13615

Keywords:

Terbinafine, Itraconazole, Treatment outcome, Tinea pedis

Abstract

Background: Tinea pedis (athlets foot) is the most common fungal infection. Relapse is common in tinea pedis and may be result of recurrence following inadequate treatment or reinfection.

Objective: To evaluate the comparable efficacy of terbinafine and itraconazole in the treatment of tinea pedis.

Methods: 120 patients of tinea pedis confirmed by KOH microscopy were included in the study. The study was carried out in three different Hospitals and Private Chambers for a period of 3 years from July 2006 to June 2009. Mean age of the patients was 40.28±10.23. The patients were devided into 2 equal group:A & B. Group- A was given terbinafine 250 mg/day and group-B was given intraconazole 200 mg/day for 2 weeks.

Results: Follow up 2 weeks after cessation of therapy revealed clinical and mycological cure of 93.3% in terbinafine group and 86.6% in itraconazole group.

Conclusion: Efficacy analysis revealed that terbinafine is superior than itraconazole in the treatment of tinea pedis (P value 0.224).

DOI: http://dx.doi.org/10.3329/bjmed.v21i2.13615

Bangladesh J Medicine 2010; 21: 74-79

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Published

2013-02-03

How to Cite

Wahab, M. A., Uddin, M. J., Hassan, B. S., Islam, M. Z., Bhuiyan, I., & Siddique, M. R. U. (2013). Comparable Efficacy of Terbinafine and Itraconazole in the Treatment of Tinea Pedis. Bangladesh Journal of Medicine, 21(2), 74–79. https://doi.org/10.3329/bjmed.v21i2.13615

Issue

Vol. 21 No. 2 (2010)

Section

Original Articles