The Relationship Between BMI And Neutrophil/Lymphocyte Ratio in Non-critical Hospitalized Patients With Coronavirus Disease 2019

Authors

  • Md Shahed Morshed Emergency Medical Officer, Kurmitola General Hospital, Dhaka, Bangladesh
  • Hurjahan Banu Medical Officer, Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Nusrat Sultana Assistant Professor, Department of Endocrinology, BSMMU, Dhaka, Bangladesh
  • MA Hasanat Professor, Department of Endocrinology, BSMMU, Dhaka, Bangladesh
  • Shohael Mahmud Arafat Professor, Department of Internal Medicine, BSMMU, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjm.v34i1.63425

Keywords:

Coronavirus disease 2019, body mass index, obesity, neutrophil/lymphocyte ratio

Abstract

Background: People with obesity may be adversely affected by Coronavirusdisease 2019 (COVID-19). The objective of the study was to assess the clinical and biochemical characteristics of non-critical hospitalized patients of COVID-19 with obesity.

Methods: This cross-sectional observational study was done among 88 non-critical hospitalized patients of COVID-19 [age: 50.0 (33.50-60.0) years, median (IQR); m/f: 36/52). The severity of COVID- 19 at diagnosis was determined by WHO interim guidance on COVID-19, 2000, and obesity was defined by a body mass index of 25 kg/m2. Clinical and biochemical information at diagnosis were collected in a data sheet.

Results: Around 34% of the patients had obesity. Baseline characteristics and clinical features were statistically similar between obese and non-obese patients (NS for all). Among biochemical features, only total leukocytes (p=0.007), absolute neutrophils count (p=0.001), and neutrophils/ lymphocytes ratio (p=0.002) were significantly lower in obese patients than non-obese patients. Body mass index (BMI) had significant negative correlations with total leukocytes (r=-0.318, p=0.005), absolute neutrophil count (r=-370, p=0.001) and neutrophils/lymphocytes ratio (r=-0.349, p=0.002) in the study population.

Conclusion: BMI had inverse associations with total leukocytes, absolute neutrophil count, and neutrophil/lymphocyte ratio among non-critical hospitalized patients with COVID-19.

Bangladesh J Medicine 2022; 33: 36-42

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Published

2022-12-29

How to Cite

Morshed, M. S., Banu, H. ., Sultana, N. ., Hasanat, M. ., & Arafat, S. M. . (2022). The Relationship Between BMI And Neutrophil/Lymphocyte Ratio in Non-critical Hospitalized Patients With Coronavirus Disease 2019. Bangladesh Journal of Medicine, 34(1), 36–42. https://doi.org/10.3329/bjm.v34i1.63425

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Section

Original Articles