Seroprevalence of Mumps IgG Antibody among Health Care Workers in Relation with Sociodemographic Change at A Tertiary Care Hospital in Bangladesh

Abstract

Background: Mumps is a major problem worldwide as it highly contagious in region where population density is more. However, mumps was an early childhood illness, now a day it affects adolescents and young adults.

Objective: The purpose of the present study was to evaluate the immune status of mumps among health care worker by determining the anti-mumps antibody (IgG) level in a tertiary care hospital of Bangladesh.

Methodology: This cross-sectional observational study was conducted in the Department of Microbiology, Sylhet MAG Osmani Medical College, Sylhet, Bangladesh during the period from 1st January 2018 to 31st December 2018. By convenient sampling apparently healthy adult individuals (n=120) were selected according to enrollment criteria. Healthy adult health care worker (age between 18-45 years and any gender) were included. Serum IgG antibody against Mumps were measured by ELISA method following the instructions provided by manufacturer’s package insert. All data were processed and analyzed with the help of SPSS (Statistical Package for Social Sciences) Version 21.0.

Results: Total 180 participants were recruited in this study. The age of the participants ranged from 18 to 45 years with the mean ± SD age of 28.54± 7.74 years. Protective immunity against mumps was found more in male which was 55 (70.51%). The highest mean serum IgG level was 1.48± 0.64 in urban participants, the lower socioeconomic group (1.59 ± 0.59) and the student’s group (1.63 ± 0.71). The mean serum IgG level was significantly higher among participants with a history of mumps infection (2.10 ± 0.12) and participants with a history of close contact with mumps infection had a higher mean serum IgG level (1.69 ± 0.57) than those without a history of close contact (1.44 ± 0.62), and this difference was statistically significant (F = 6.160; p = 0.014).

Conclusion: In conclusion, significant number of participants remains unprotected against mumps. Countries that have low immunization rates, people are more vulnerable to mumps infection especially young adult age group.

Bangladesh Journal of Medical Microbiology, January 2026;20 (1):39-45