Study of antimicrobial susceptibility of clinically significant microorganisms isolated from selected areas of Dhaka, Bangladesh

Authors

  • Subarna Dutta Department of Microbiology, Stamford University Bangladesh, Dhaka and Ibrahim Medical College & Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders (BIRDEM) Hospital, Shahbag, Dhaka
  • Md Rokibul Hassan Department of Microbiology, Stamford University Bangladesh, Dhaka and Ibrahim Medical College & Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders (BIRDEM) Hospital, Shahbag, Dhaka
  • Farjana Rahman Department of Microbiology, Stamford University Bangladesh, Dhaka
  • Md Shariful Alam Jilani Ibrahim Medical College & Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders (BIRDEM) Hospital, Shahbag, Dhaka
  • Rashed Noor Department of Microbiology, Stamford University Bangladesh, Dhaka

DOI:

https://doi.org/10.3329/bjms.v12i1.13351

Keywords:

Pathogens, drug resistance, Extended spectrum b- lactamase (ESBL), Methicillin resistant Staphylococcus aureus (MRSA), Methicillin resistant S. epidermidis (MRSE)

Abstract

Objective: Pathogenic resistance against antibiotics is substantially mounting in the developing countries including Bangladesh. Present study thus attempted to obtain the baseline information on such resistance among the community people coming to the local dispensaries around the city of Dhaka for treatment.

Materials and Methods: A total of 2,700 clinical specimens were examined for the presence of Gram positive and Gram negative pathogens. Antibiotic susceptibility tests of the isolates were carried out. Extended spectrum b- lactamase (ESBL) activity, and the presence of methicillin resistant Staphylococcus aureus (MRSA) and S. epidermidis (MRSE) were also detected.

Results: Escherichia coli were most prevalent (45.5%) among 1044 pathogenic bacteria isolated from 2,700 samples. E. coli predominated urine, pus, wound swab, blood, high vaginal swab (HVS) and sputum specimens, and exhibited the highest frequency of ESBL activity (35%). Prevalence of Klebsiella spp. and S. aureus among the clinical specimens were 11.5% and 9.86%, respectively. Most of the Gram negative bacilli were found resistant against ciprofloxacin (5 mg), tetracycline (30 mg) and cotrimoxazole (25 mg). Majority of Pseudomonas spp. were found resistant against most of the commonly used antibiotics. Interestingly, around half of the S. aureus isolates were observed to be methicillin resistant, but not vancomycin resistant.

Conclusion: Overall, such a revelation of increased antibiotic resistance demands for restrictive and appropriate antibiotic usage in accordance with the updated antibiotic prescribing policy in Bangladesh.

DOI: http://dx.doi.org/10.3329/bjms.v12i1.13351

Bangladesh Journal of Medical Science Vol. 12 No. 01 January13 pp.34-42

Downloads

Download data is not yet available.
Abstract
400
PDF
125

Downloads

Published

2013-01-17

How to Cite

Dutta, S., Hassan, M. R., Rahman, F., Jilani, M. S. A., & Noor, R. (2013). Study of antimicrobial susceptibility of clinically significant microorganisms isolated from selected areas of Dhaka, Bangladesh. Bangladesh Journal of Medical Science, 12(1), 34–42. https://doi.org/10.3329/bjms.v12i1.13351

Issue

Vol. 12 No. 1 (2013)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.