Combination therapy in hemiballismus-hemichorea syndromes - a report of two cases

Authors

  • Vikas Mishra Bombay Hospital Institute of Medical Sciences, Mumbai
  • Suresh Jain Bombay Hospital Institute of Medical Sciences, Mumbai
  • Jehangir Sorabjee Bombay Hospital Institute of Medical Sciences, Mumbai

DOI:

https://doi.org/10.3329/bjms.v13i4.17536

Keywords:

hemiballismus-hemichorea, tetrabenzine, haloperidol, valproate, combination therapy

Abstract

Hemiballismus-hemichorea is an uncommon disorder. In the past, patients developing hemiballismus and hemichorea were considered to have poor prognosis with high morbidity and even mortality at times. While majority of patients of hemiballismus go into spontaneous remission, some severe cases require prolonged treatment. We here describe two such cases of which one presented to us with post stroke hemiballismus, unresponsive to monotherapy and the other was an HIV positive patient with unresponsive hemichorea secondary to CNS toxoplasmosis. Both these patients responded well when combination therapy was instituted and had normal recovery.

DOI: http://dx.doi.org/10.3329/bjms.v13i4.17536

Bangladesh Journal of Medical Science Vol.13(4) 2014 p.484-487

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Author Biographies

Vikas Mishra, Bombay Hospital Institute of Medical Sciences, Mumbai

Resident (MD), Department of Medicine

Suresh Jain, Bombay Hospital Institute of Medical Sciences, Mumbai

Consultant Physician, Department of Medicine

Jehangir Sorabjee, Bombay Hospital Institute of Medical Sciences, Mumbai

Professor and Head, Department of Medicine

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Published

2014-09-27

How to Cite

Mishra, V., Jain, S., & Sorabjee, J. (2014). Combination therapy in hemiballismus-hemichorea syndromes - a report of two cases. Bangladesh Journal of Medical Science, 13(4), 484–487. https://doi.org/10.3329/bjms.v13i4.17536

Issue

Section

Case Reports