Early diagnosis of neonatal sepsis in primary health care unit

Authors

  • Aditya Prasad Sarkar Associate Professor, Community Medicine, Bankura Sammilani Medical College, Bankura, West Bengal
  • Goutam Dhar Associate Professor, Community Medicine & Deputy Director, West Bengal Medical Education Service, Government of West Bengal
  • Munmun Das Sarkar Assistant Professor, Microbiology & Assistant Secretary, West Bengal Medical Education Service, Government of West Bengal
  • Tapan Kumar Ghosh Department of Pathology, Bankura Sammilani Medical College, Bankura, West Bengal
  • Sulekha Ghosh Professor, Department of Pathology, Bankura Sammilani Medical College, Bankura, West Bengal

DOI:

https://doi.org/10.3329/bjms.v14i2.21806

Keywords:

neonatal sepsis, micro-ESR, I/T ratio

Abstract

Aim: The aim of the study is to find out the role of common haematological parameters along with micro-ESR, I/T ratio in diagnosis of neonatal sepsis for initiating early management.

Methods: This is a descriptive study consisting of 35 neonates admitted at a sophisticated institute with clinical suspicion of septicaemia along with 40 neonates as the comparison group. The neonatal haematological parameters including total leucocytes count, absolute neutrophil count, immature neutrophil count, I/T ratio, platelet count were measured in all the neonates. Micro-ESR was measured as a bed side test. CRP was also measured using slide agglutination method and the results were compared with turbidimetric method. Blood culture was done as a gold standard test for sepsis. Micro-ESR more than age of the patient in days +3 mm in 1st hour was considered significant for sepsis. I/T ratio more than or equal to 0.2 was considered positive for sepsis.

Results: The study revealed that micro-ESR and I/T ratio were significantly higher (p<0.001) in suspected cases of septicaemia as compared to the neonates in the comparison group. Sensitivity and specificity of micro-ESR were 87.09% and 75.0% respectively. Sensitivity and specificity of I/T ratio were 93.54% and 95% respectively.

Conclusion: Micro-ESR and I/T ratio can be used effectively as cheap and simple tests to screen for septicaemia in neonate which is possible even in a primary health care centre.

Bangladesh Journal of Medical Science Vol.14(2) 2015 p.169-172

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Published

2015-04-18

How to Cite

Sarkar, A. P., Dhar, G., Sarkar, M. D., Ghosh, T. K., & Ghosh, S. (2015). Early diagnosis of neonatal sepsis in primary health care unit. Bangladesh Journal of Medical Science, 14(2), 169–172. https://doi.org/10.3329/bjms.v14i2.21806

Issue

Vol. 14 No. 2 (2015)

Section

Original Articles

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