Correlation of Lipoprotein (a) Level with Complexity of Coronary Lesion in Coronary Heart Disease Patient at RSUP Dr. Sardjito Yogyakarta

Authors

  • Iin Novita Nurhidayati Mahmuda Department Internal medicine, Faculty of Medicine, Muhammadiyah University of Surakarta
  • Lucia Kris Dinarti Department of Cardiologi-Internal Medicine, Faculty of Medicine Gadjah Mada University
  • Nahar Taufiq Department of Cardiologi-Internal Medicine, Faculty of Medicine Gadjah Mada University

DOI:

https://doi.org/10.3329/bjms.v15i3.30190

Keywords:

coronary heart disease, lipoprotein (a), complexity coronary vessel lesion, SYNTAX Score, correlation

Abstract

Background: In 2020 there were estimated to be 25 million deaths each year from cardiovascular disease; most of them being coronary heart disease. Traditional risk factors such as smoking, hypertension, diabetes, dyslipidemia reported to affect only 50% of the prevalence and degree of coronary heart disease. It pushes a lot of research on non-traditional risk factors one of which is lipoprotein (a). Levels of Lp (a) also reflects the degree of severity and is associated with the number of coronary arteries involved. The purpose of this study was to determine the relationship of Lp (a) level with the complexity of coronary artery lesion.

Methods: This was a cross-sectional study. Subjects were male and women patients aged between 20 to 60 years who underwent coronary angiography for theirs STEMI, NSTEMI, unstable angina pectoris, and stable angina pectoris. Correlation between elevated Lp (a) with the complexity of coronary artery lesion was performed by Pearson test. If the distribution was abnormal we used Spearman test.

Result: Number of samples was 64 subjects (49 men and 15 women). The result showed a significant positive correlation between Lp (a) level and complexity of coronary vessel lesion that counted by SYNTAX score (p 0,004) even though the coefficient correlation is weak (r 0, 33).

Conclusion: The higher Lp (a) level shows bigger SYNTAX score which means the coronary vessel lesion more complex.

Bangladesh Journal of Medical Science Vol.15(3) 2016 p.362-367

Downloads

Download data is not yet available.
Abstract
1
PDF
1

Author Biography

Iin Novita Nurhidayati Mahmuda, Department Internal medicine, Faculty of Medicine, Muhammadiyah University of Surakarta



Downloads

Published

2016-11-03

How to Cite

Mahmuda, I. N. N., Dinarti, L. K., & Taufiq, N. (2016). Correlation of Lipoprotein (a) Level with Complexity of Coronary Lesion in Coronary Heart Disease Patient at RSUP Dr. Sardjito Yogyakarta. Bangladesh Journal of Medical Science, 15(3), 362–367. https://doi.org/10.3329/bjms.v15i3.30190

Issue

Vol. 15 No. 3 (2016)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.