Antimicrobial sensitivity patterns of salmonella typhi in children

Authors

  • Md Khoyber Ali Associate Professor & Head, Dept of Paedilatrics, Ibn Sina Medical College, Dhaka
  • Shahin Sultana Professor, Dept of Microbiology, Delta Medical College, Dhaka

DOI:

https://doi.org/10.3329/bjms.v15i3.30198

Keywords:

multidrug resistant, typhoid fever

Abstract

Background: Enteric fever is an important public health problem in developing countries including Bangladesh. A changing antibiotic sensitivity pattern of Salmonella typhi and emergence of resistance has increased to a great concern.

Objective: Aim of the study was to investigate the antibiotic sensitivity pattern of Salmonella typhi.

Methods: A total of 181 Salmonella typhi samples from 5 to 15 years age group were collected from blood culture during the period of October to December 2014 from IBN SINA Hospital, Dhaka, Bangladesh. Specimens from the blood culture were identified by standard procedures as needed. Antimicrobial susceptibility testing was performed by disk diffusion method according to The Clinical Laboratory Standard Institute guidelines.

Results: Among the tested antibiotics, S. typhi was susceptible to ceftriaxone 100%, followed by cefixime and gentamicin 99.4%, ciprofloxacin 98.6%, cotrimoxazole 88.9%, azithromycin 88.4 % and least susceptible antibiotic was Ampicillin 62.5% and nalidixic acid 5%. Conclusion: The antimicrobial sensitivity testing showed that the Salmonella typhi were highly sensitive (>88%) to most of the drugs used in this study, whereas nalidixic acid showed only 5% sensitivity. So this study indicates that ceftriaxone, cefixime, gentamicin and ciprofloxacin can be used as a first line therapy and nalidixic acid should be avoided for treatment.

Bangladesh Journal of Medical Science Vol.15(3) 2016 p.416-418

Downloads

Download data is not yet available.
Abstract
23
PDF
29

Author Biography

Md Khoyber Ali, Associate Professor & Head, Dept of Paedilatrics, Ibn Sina Medical College, Dhaka



Downloads

Published

2016-11-03

How to Cite

Ali, M. K., & Sultana, S. (2016). Antimicrobial sensitivity patterns of salmonella typhi in children. Bangladesh Journal of Medical Science, 15(3), 416–418. https://doi.org/10.3329/bjms.v15i3.30198

Issue

Vol. 15 No. 3 (2016)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.