Efficacy of Ayarij Faiqura in Qarah-e-Hazmiya - Randomized controlled Clinical study

Authors

  • MA Siddiqui HoD of Moalajat & Director, National Institute of Unani Medicine-Bengaluru-91
  • Abdul Quavi Dept. of Surgery, Government Unani Medical College, Allahabad-16
  • Mohd Aleemuddin Quamri Reader, Dept. of Moalajat, National Institute of Unani Medicine-Bengaluru-91

DOI:

https://doi.org/10.3329/bjms.v17i1.35291

Keywords:

Qarah-e-Hazmiya, PUD, Ayarij Faiqura, Pantoprazole, Unani Medicine

Abstract

Background and Objective: Qarahe Hazmiya (Peptic ulcer disease) is one of the commonest ailment of Gastro intestinal tract, reported to affect around 4% of the population and 10% of people developed it at some point in their life. Etiopathology of the disease is considered as multi factorial mostly treated with medications and rarely with surgery. Several Unani formulation have been indicated effective in Qarahe Hazmiya, one of such formulation has been selected to evaluate its efficacy and to validate the same on scientific parameters

Methods: This study was conducted as a single blind, randomized standard control clinical trial on 28 patients (n=20) in test and (n=8) control groups. Test group received Ayarij Faiqura 5gm and control group received Pantoprazole 40 mg, orally in empty stomach for 45 days. The study outcome was assessed as the difference in pre and post treatment through subjective and objective parameters.

Result: The test drugs revealed statistically significant improvement in burning sensation in abdomen (p<0.0001), pain abdomen (p<0.0001) as subjective parameters in comparison to control group where as objectivecally endoscopic report showed significantly improvement (p<0.0196) in comparison to control group with respect to the healing of ulcer / erosions.

Interpretation and conclusion: The study revealed that the test drug had good response in controlling burning sensation and pain abdomen, along with healing of ulcer / erosions in comparison to control drug. No side effect or toxicity was observed during and or after the study. Thus, it could be concluded that the test drug was found to be safe and effective without any adverse effect.

Bangladesh Journal of Medical Science Vol.17(1) 2018 p.112-117

Downloads

Download data is not yet available.
Abstract
15
PDF
24

Downloads

Published

2018-01-11

How to Cite

Siddiqui, M., Quavi, A., & Quamri, M. A. (2018). Efficacy of Ayarij Faiqura in Qarah-e-Hazmiya - Randomized controlled Clinical study. Bangladesh Journal of Medical Science, 17(1), 112–117. https://doi.org/10.3329/bjms.v17i1.35291

Issue

Vol. 17 No. 1 (2018)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.