“Human Papilloma Virus Vaccination for cervical cancer prevention. Is it safe and effective?”

Authors

  • Damitha Asanga Gunawardane Post MD Trainee in Community Medicine, Department of Community Medicine, Faculty of Medicine, University of Peradeniya

DOI:

https://doi.org/10.3329/bjms.v17i3.36985

Abstract

Human papillomavirus (HPV) causes cervical cancer, which is the fourth most common cancer in women. Most of the cervical cancers are linked to genital infection with HPV and it is the most common viral infection of the reproductive tract. At present, there are three types of HPV vaccines available. Even though HPV vaccination is a primary prevention tool, that does not eliminate the need for routine cervical screening, since the vaccines do not protect against all high-risk HPV types. Ninety percent of HPV infections have no clinical consequences at all whether they are high-risk or low-risk subtypes of HPV. All three types of HPV vaccines have very high vaccine efficacy for prevention of HPV infection among females aged 14 to 26 years. Proper assessment of the safety of HPV vaccine is a problem even after proper systematic review since the most of the clinical trials on the safety of the vaccines were used Hepatitis A vaccine or high immunogenicity enhancing aluminium adjuvant as their placebo. HPV vaccination would be very cost effective for the countries when there is no cervical screening program or if the programme coverage is very poor.

Bangladesh Journal of Medical Science Vol.17(3) 2018 p.329-336

Downloads

Download data is not yet available.
Abstract
2350
PDF
1831

Author Biography

Damitha Asanga Gunawardane, Post MD Trainee in Community Medicine, Department of Community Medicine, Faculty of Medicine, University of Peradeniya



Downloads

Published

2018-06-29

How to Cite

Gunawardane, D. A. (2018). “Human Papilloma Virus Vaccination for cervical cancer prevention. Is it safe and effective?”. Bangladesh Journal of Medical Science, 17(3), 329–336. https://doi.org/10.3329/bjms.v17i3.36985

Issue

Vol. 17 No. 3 (2018)

Section

Review Article

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.