An unusual case of Essential Thrombocythemia in coexistence with Breast cancer

Authors

  • Charu Agarwal Associate Professor, Dept. of Pathology, ESIC Medical College, aridabad, Haryana, India
  • Mukta Pujani Professor, Dept. of athology, ESIC Medical College, Faridabad, Haryana, India
  • Novak Gupta Medical Oncologist, Dept. of Medicine, ESIC Medical College, Faridabad, Haryana, India
  • Varsha Chauhan Assistant Professor, Dept. of Pathology, ESIC Medical College, Faridabad, Haryana, India
  • Sujata Raychaudhuri Professor, Dept. of Pathology, ESIC Medical College, Faridabad, Haryana, India
  • Ruchira Wadhwa Senior Resident, Dept. of Pathology, ESIC Medical College, Faridabad, Haryana, India

DOI:

https://doi.org/10.3329/bjms.v21i2.58083

Keywords:

Essential thrombocythemia; breast cancer; JAK 2 mutation; coexistence

Abstract

Essential thrombocythemia (ET) is an extremely rare myeloproliferative neoplasm (MPN) which is characterized by persistent, non-reactive thrombocytosis (> 450 X 109/L) and an increased risk for thrombotic events.These patients have an increased risk of both hematological and non-hematological malignancies however the risk of breast cancer in MPN is not increased in comparison to general population. We hereby present an extremely unusual case of ET in a 38 years old female (diagnosed with breast cancer), which came to light on routine pre-surgical work up of the patient.Diagnosis was confirmed on bone marrow aspiration clubbed with JAK 2 mutation. Patients with ET have an increased risk of thrombosis thereby it becomes challenging for the clinician to operate on a coexistent solid tumor. On extensive literary search, there was a single case of coexistent Breast Cancer and Essential Thrombocythemia and we are reporting second such coexistence to the best of our knowledge.

Bangladesh Journal of Medical Science Vol. 21 No. 02 April’22 Page : 463-466

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Published

2022-02-25

How to Cite

Agarwal, C. ., Pujani, M. ., Gupta, N. ., Chauhan, V. ., Raychaudhuri, S. ., & Wadhwa, R. . (2022). An unusual case of Essential Thrombocythemia in coexistence with Breast cancer. Bangladesh Journal of Medical Science, 21(2), 463–466. https://doi.org/10.3329/bjms.v21i2.58083

Issue

Vol. 21 No. 2 (2022)

Section

Case Reports

License

Copyright (c) 2022 Charu Agarwal, Mukta Pujani, Novak Gupta, Varsha Chauhan, Sujata Raychaudhuri, Ruchira Wadhwa

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