The Concomitant Use of Melatonin and Molnupiravir in the Treatment of COVID-19: Mini Review

Authors

  • Ismail Celil Haskologlu Department of Pharmacology, Faculty of Pharmacy, Near East University, Nicosia, Cyprus
  • Emine Erdag Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Near East University, Nicosia, Cyprus
  • Serkan Sayiner Department of Biochemistry, Faculty of Veterinary Medicineand Diagnostic Laboratory, Animal Hospital, Near East University, Nicosia, Cyprus
  • Merve Mercan Department of Pharmacology, Faculty of Pharmacy, Near East University, Nicosia, Cyprus
  • Ugochukwu Chukwunyere Department of Pharmacology, Faculty of Pharmacy, Near East University, Nicosia, Cyprus
  • Nurettin Abacioglu Department of Pharmacology, Faculty of Pharmacy, Near East University, Nicosia, Cyprus
  • Ahmet Ozer Sehirli Department of Pharmacology, Faculty of Dentistry, Near East University, Nicosia, Cyprus.

DOI:

https://doi.org/10.3329/bjms.v22i1.61857

Keywords:

Molnupiravir; melatonin; cytokine; SARS-CoV-2; COVID-19

Abstract

With the ongoing pandemic declared by the World Health Organization,the number of hospitalizations and deaths caused by COVID-19 is increasing dramatically. As new variants of SARS-CoV-2 emerge, new combination therapies are needed to reduce the risk of COVID- 19spreadduring this time of increased transmission risk. In this case, it is vitalto strengthen the immune system against highly inflammatory conditions such as the cytokine storm caused by COVID-19. This brief review highlights the benefits of taking melatonin and the new antiviral drug molnupiravir together in the treatment of COVID-19. Webelieve that this combination therapy against COVID-19 would be of great benefit and should be considered as an adjuvant therapy in the treatment of this disease.

Bangladesh Journal of Medical Science Vol. 22 No. 01 January’23 Page : 32-37

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Published

2023-01-01

How to Cite

Haskologlu, I. C. ., Erdag, E. ., Sayiner, S. ., Mercan, M., Chukwunyere, U. ., Abacioglu, N. ., & Sehirli, A. O. (2023). The Concomitant Use of Melatonin and Molnupiravir in the Treatment of COVID-19: Mini Review. Bangladesh Journal of Medical Science, 22(1), 32–37. https://doi.org/10.3329/bjms.v22i1.61857

Issue

Section

Review Article