Diverted Mini Gastric Bypass Surgery in Obese Population: Out-turn Over Hepatic and Nephrological Parameters

Authors

  • Arya Singh Asian Bariatrics Plus Hospital, V wing- Mondeal Business Park, S G Highways, Ahmedabad-380054, India
  • Rahnuma Ahmad Department of Physiology, Medical College for Women and Hospital, Dhaka, Bangladesh
  • Susmita Sinha Department of Physiology, Khulna City Medical College and Hospital, 33 KDA Avenue, Hotel Royal Crossing, Khulna Sadar, Khulna 9100, Bangladesh
  • Susmita Sinha Department of Physiology, Khulna City Medical College and Hospital, 33 KDA Avenue, Hotel Royal Crossing, Khulna Sadar, Khulna 9100, Bangladesh
  • Md Ahsanul Haq Infectious Diseases Division, icddr, b, Mohakhali, Dhaka-1212, Bangladesh
  • Mahendra Narwaria Asian Bariatrics Plus Hospital, V wing- Mondeal Business Park, S G Highways, Ahmedabad-380054, India
  • Mainul Haque The Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, Malaysia, Department of Scientific Research Center (KSRC) Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat-382422. India
  • Santosh Kumar Department of Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat-382422. India
  • Nandita Sanghani Department of Biochemistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat-382422. India

DOI:

https://doi.org/10.3329/bjms.v22i4.68669

Keywords:

Bariatric surgery, Obesity, inflammation, organ damage, weight loss, health benefit, renal function, liver function

Abstract

Introduction: Bariatric surgery is the best possible option for reducing weight when lifestyle changes and medication have not brought about lasting success and may reduce morbidity and mortality. Weight loss that may follow bariatric surgery in patients on calory restricted diet would result in reduced inflammation and therefore lowering inflammation-related organ damage, including that of the kidney and liver. The study aimed to observe the consequences of BMI change on Hepatic and Nephrological parameters in patients after One Anastomosis Gastric Bypass surgery. Method: This study was done at a bariatric center with 150 individuals (both male and female) aged 20 to 60 years with obesity grades II and III who were selected randomly. Hepatic and renal function tests were carried out at baseline visit, then 3 months and 6 months following surgically. Result: Bilirubin level significantly increased from baseline to visit 1; Serum glutamic-pyruvic transaminase (SGPT) levels significantly decreased at visits 1 and 2. The albumin to Globulin ratio was significantly increased at visit 2 . Blood Urea level and serum creatinine level reduced considerably at visit 1 and decreased more at visit 2 from baseline. Conclusion: Bariatric surgery may be related to improvement in both hepatic and renal function. The improvement may be attributed to reduced inflammatory organ damage related to obesity. More such studies must be performed to highlight the possible health benefits of bariatric surgery for obese patients whose lifestyle modification and medication have not aided in weight loss.

Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 743-758

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Published

2023-09-07

How to Cite

Singh, A. ., Ahmad, R. ., Sinha, S. ., Sinha, S. ., Haq, M. A. ., Narwaria, M. ., Haque, M. ., Kumar, S. ., & Sanghani, N. . (2023). Diverted Mini Gastric Bypass Surgery in Obese Population: Out-turn Over Hepatic and Nephrological Parameters. Bangladesh Journal of Medical Science, 22(4), 743–758. https://doi.org/10.3329/bjms.v22i4.68669

Issue

Vol. 22 No. 4 (2023)

Section

Original Articles

License

Copyright (c) 2023 Arya Singh, Rahnuma Ahmad, Susmita Sinha, Susmita Sinha, Md Ahsanul Haq, Mahendra Narwaria, Mainul Haque, Santosh Kumar, Nandita Sanghani

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