Mini Gastric Bypass Surgery in Obese Population: Impact on Lipid profile

Authors

  • Arya Singh Asian Bariatrics Plus Hospital, V wing- Mondeal Business Park, S G Highways, Ahmedabad-380054, India
  • Susmita Sinha Department of Physiology, Khulna City Medical College and Hospital, 33 KDA Avenue, Hotel Royal Crossing, Khulna Sadar, Khulna 9100, Bangladesh
  • Rahnuma Ahmad Department of Physiology, Medical College for Women and Hospital, Dhaka, Bangladesh
  • Md Ahsanul Haq Pallirup, Safugta, Mirpur, Dhaka 1216, Bangladesh
  • Mahendra Narwaria Asian Bariatrics Plus Hospital, V wing- Mondeal Business Park, S G Highways, Ahmedabad-380054, India
  • Ankur Sharma Department of General & Advanced laparoscopic surgery, Tagore Hospital & Heart Care center, Jalandhar-144008. India
  • Mainul Haque Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, Malaysia
  • Santosh Kumar Department of Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat-382422. India
  • Nandita Sanghani Department of Biochemistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat-382422. India

DOI:

https://doi.org/10.3329/bjms.v23i2.72141

Keywords:

Bariatric surgery, Obesity, inflammation, organ damage, weight loss, health benefit, renal function, liver function

Abstract

Introduction  Obesity has became a significant health concern over the past decade. According to a higher body mass index (BMI), obesity enhances the probability of malignancy, type 2 diabetes mellitus, cardiac disorders, and musculoskeletal diseases. Bariatric surgery, a typical and effective surgical intervention for patients with excess body weight with concurrent medical conditions, achieves significant weight loss over a long period. Numerous studies have been conducted on the effectiveness of various bariatric surgery techniques for improving glycemic homeostasis and helping patients lose weight. However, little is known about how bariatric surgery affects the lipid profile. The study aims to determine how patients’ altered BMI affects lipid parameters following OAGB/MGB surgery.

Methods  To achieve this, the longitudinal observational study was conducted from January 2021 to January 2022 among 150 patients scheduled to undergo Anastomosis Gastric Bypass Surgery. The mean age of the patients was 41.7 years, with a standard deviation of 14.7 years (mean±SD: 41.7±14.7). Among the study participants, 56 individuals (37.3%) were male, while 94 (62.7%) were female.

Objectives  Regarding comorbidities, hypertension was identified as the most prevalent condition among the enrolled patients, affecting 49.3% of them.

Results  It was observed that the levels of S. Cholesterol and S. Triglyceride showed a significant decrease after one month (Visit-1) of the bypass surgery, with a reduction of 21.8 mg/dl (95% CI=-31.9, -11.6, p=<0.001) and 14 mg/dl (95% CI=-25.5, -2.51, p=0.017), respectively

Conclusion  OAGB outcome is associated with a healthier lipid profile and enhanced weight management.

Bangladesh Journal of Medical Science Vol. 23 No. 02 April’24 Page : 327-336

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Published

2024-03-27

How to Cite

Singh, A. ., Sinha, S., Ahmad, R. ., Haq, M. A. ., Narwaria, M., Sharma, A., Haque, M., Kumar, S., & Sanghani, N. (2024). Mini Gastric Bypass Surgery in Obese Population: Impact on Lipid profile. Bangladesh Journal of Medical Science, 23(2), 327–336. https://doi.org/10.3329/bjms.v23i2.72141

Issue

Vol. 23 No. 2 (2024)

Section

Original Articles

License

Copyright (c) 2024 Arya Singh, Susmita Sinha, Rahnuma Ahmad, Md Ahsanul Haq, Mahendra Narwaria, Ankur Sharma, Mainul Haque, Santosh Kumar, Nandita Sanghani

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