Prognostic role of C-reactive protein in acute stroke

Authors

  • MM Rahman Department of Biochemistry, Pabna Medical College, Pabna
  • MA Rabim Department of Biochemistry, Community Medical College, Rangpur
  • RK Nath Department of Biochemistry, Kumidini Medical College, Tangail
  • AK Al-Mahmood Department of Biochemistry, Ibn Sina Medical College, Dhaka.
  • FH Mollah Department of Biochemistry, Ibn Sina Medical College, Dhaka

DOI:

https://doi.org/10.3329/bjms.v10i1.7316

Keywords:

C-reactive protein

Abstract

Background & objective: Stroke is a dreadful health hazard all over the world as well as in our country and one of the leading causes of mortality & morbidity. The relationship between serum C-reactive protein (CRP) level and post stroke outcome is not well studied especially in Bangladesh. We were interested to study this relationship in our country.

Materials & methods: A cross sectional prospective study was performed on 50-stroke patients. Serum CRP & Lipid profile was determined. Post stroke outcome was measured by modified ranking scale (good outcome, score within 0 – 2 & bad outcome, score within 3 – 6). The subjects were divided in two groups, CRP level above or below 10 mg/L. Statistical analysis was performed by using SPSS software. Chi-square test & Spearman’s rho correlation test was done to see the level of significance.

Results: Mean serum CRP level was 9.69 mg/L that was higher than normal subjects. Correlation analysis between serums CRP level of stroke patients with post stroke outcome was found to be positively correlated (r = 0.598/p<0.01).

Conclusion: Serum CRP level may be used as a prognostic marker in stroke patients and it helps to make necessary management plan to physician.

DOI: 10.3329/bjms.v10i1.7316

Bangladesh Journal of Medical Science Vol.10 No.1 Jan 2010 pp.29-33

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How to Cite

Rahman, M., Rabim, M., Nath, R., Al-Mahmood, A., & Mollah, F. (2011). Prognostic role of C-reactive protein in acute stroke. Bangladesh Journal of Medical Science, 10(1), 29–33. https://doi.org/10.3329/bjms.v10i1.7316

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Original Articles