Scientific Justification of A Personalized Approach To The Management of Patients with Terminal Renal Failure

Authors

  • Otynshiyeva Shynar Abdigapparkyzy Doctor-therapis, PhD student of the Department of Propaedeutics of internal diseases South Kazakhstan medical academy, Shymkent, Kazakhstan,
  • Narmanova Oryngul Zhaksybayevna Professor of the department of public health NPJSC “ASTANA MEDICAL UNIVERSITY” Doctor of medicine, nephrologist
  • Assel Sadykova PhD, Post Doc, Ass. Professor, Al-Farabi Kazakh National University
  • Karlygash Tazhibayeva PhD, PostDoc, MD, Ass.Professor, Al-Farabi Kazakh National University, Al-Farabi Kazakh National University, Asfendiyarov Kazakh National Medical University, Oncologistgynecologist of Almaty Regional Multidisciplinary Clinic
  • Abenova Moldir Doctor-Pediatric, Master of Medical Sciences Chief Specialist of the Department for the Development of the Formulary System and Professional Expertise of Medicines and Medical Devices Department for Improving the Medicines Policy of the RSE at the REM “National Scientific Research Center for Healthcare named after Salidat Kairbekova” of the Ministry of Health of the Republic of Kazakhstan Kazakhstan, Astana
  • Kemelbekov Kanatzhan MD., PhD, Associate Professor Head of the Department of Pediatrics-1, South Kazakhstan medical academy,Shymkent, Kazakhstan
  • Baimakhanova Bakhtygul ssociate Professor South Kazakhstan medical academy, Department of Pediatrics- 1,Shymkent, Kazakhstan
  • Akzhol Darhan Assistante of the Department of Propaedeutics of internal diseases South Kazakhstan medical academy,Shymkent, Kazakhstan
  • Bekmurzaeva Elmira Doctor of Medical Sciences, Professor, Department of Propaedeutics of internal diseases South Kazakhstan medical academy,Shymkent, Kazakhstan

DOI:

https://doi.org/10.3329/bjms.v23i3.75119

Keywords:

personalized approach, end stage, innovation, hemodialysis, peritoneal dialysis, transplantation.

Abstract

Currently, there is uncertainty about the ideal treatment for recovery and a personalized approach to the management of patients with terminal renal failure.Therefore, a systematic review was conducted over the past 10 years.Network meta-analysis of randomized control trials (RCTS), which compared the prevalence of chronic renal failure (CRF), according to various literature data. AccordingtoWHOitisfrom 50 to 250 peopleper 1 millionpopulationperyear.Active therapy for terminal CRF (hemodialysis, peritoneal dialysis, kidney transplantation) is received in Western Europe by 500-600 patients, in the USA and Japan - 1000-1200 patients, while in Kazakhstan-about 100 patients per 1 million population per year. The ten-year probability of survival of patients with terminal CRF in active therapy exceeds 50%, excluding patients with diabetes mellitus.Arterial hypertension remains the most frequent symptom, largely determining the prognosis of patients with CRF. Ten-year survival of patients with CRF in combination with hypertension in hemodialysis is lower than in normotensive patients by 30-50%. Successfully performed a kidney transplant can eliminate the symptoms of chronic renal failure.

Bangladesh Journal of Medical Science Vol. 23 No. 03 July’24 Page : 851-863

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Published

2024-07-29

How to Cite

Abdigapparkyzy, O. S., Zhaksybayevna, N. O., Sadykova, A., Tazhibayeva, K., Moldir, A., Kanatzhan, K., Bakhtygul, B., Darhan, A., & Elmira, B. (2024). Scientific Justification of A Personalized Approach To The Management of Patients with Terminal Renal Failure. Bangladesh Journal of Medical Science, 23(3), 851–863. https://doi.org/10.3329/bjms.v23i3.75119

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Section

Original Articles