The Role of Long Non-Coding RNAs HOTTIP, HOTAIR, and MALAT1 in Oral Squamous Cell Carcinoma

Authors

  • Abikshyeet Panda Professor, Dept of Oral Pathology and Microbiology, Kalinga Institute of Dental Sciences, KIIT deemed to be University, Patia, Bhubaneswar -751024
  • Harish Kumar Professor and HOD, Dept of Oral Pathology and Microbiology, KIIT deemed to be University, Patia, Bhubaneswar -751024
  • Tathagata Bhattacharjee Associate Professor, Department of Oral Pathology and Microbiology, Dr.R.Ahmed Dental College and Hospital. Kolkata,West Bengal.
  • T Maheswaran Professor, Department of Oral Pathology, Vivekanandha Dental College for Women, Tiruchengode-637205
  • Kailash Chandra Dash Reader, Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences, KIIT deemed to be University, Patia, Bhubaneswar -751024
  • Aishwariya Mohanty Senior Resident, Dept of Oral and Maxillofacial Pathology, S.C.B Dental College and Hospital, Cuttack- 753007

DOI:

https://doi.org/10.3329/bjms.v24i10.79173

Keywords:

Oral squamous cell carcinoma, long non-coding RNA, lncRNA, HOTTIP, HOTAIR, MALAT1, gene regulation, oral cancer, biomarkers, therapeutic targets

Abstract

When it comes to cancers of the head and neck, oral squamous cell carcinoma (OSCC) ranks high. Its complicated and poorly known molecular pathways underlie its genesis and progression. An essential role in cancer aetiology is played by long non-coding RNAs (lncRNAs), which have recently come to light as key regulators of gene expression. The purpose of this article is to offer a thorough analysis of the functions of three long non-coding RNAs (lncRNAs) in relation to oral squamous cell carcinoma: HOTTIP, HOTAIR, and MALAT1.

BJMS, Volume: 24. Supplementary Issue 2025, Page : 34-38

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Published

2025-02-11

How to Cite

Panda , A., Kumar, H., Bhattacharjee, T., Maheswaran , T., Dash, K. C., & Mohanty, A. (2025). The Role of Long Non-Coding RNAs HOTTIP, HOTAIR, and MALAT1 in Oral Squamous Cell Carcinoma. Bangladesh Journal of Medical Science, 24(10), 34–38. https://doi.org/10.3329/bjms.v24i10.79173

Issue

Vol: 24. Supplementary issue 2025

Section

Review Article

License

Copyright (c) 2025 Abikshyeet Panda , Harish Kumar, Tathagata Bhattacharjee, T. Maheswaran , Kailash Chandra Dash, Aishwariya Mohanty

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