An unusual variant of primary oral malignant myxoid melanoma with varied clinical significance

Authors

  • Pallavi Mishra Lecturer, Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences (KIDS), KIIT Deemed to be University, Patia, Bhubaneswar – 751024, Odisha, India
  • Lipsa Bhuyan Reader, Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences (KIDS), KIIT Deemed to be University, Campus-5, Patia, Bhubaneswar – 751024, Odisha, India
  • Krishna Sireesha Sundaragiri Professor, Department of Oral Pathology, RUHS College of Dental Sciences, Subash Nagar, Jaipur – 302016, Rajasthan, India
  • Prachurya Dakshinakabat Department of Oral and Maxillofacial Pathology, Geetanjali Research & Dental Institute, Geetanjali University, Udaipur – 313001, Rajasthan, India
  • Harikrishnan Prasad Professor, Department of Oral and Maxillofacial Pathology and Oral Microbiology, KSR Institute of Dental Science and Research, Tiruchengode, Tamil Nadu, India
  • Vijay Kumar Lecturer, Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences (KIDS), KIIT Deemed to be University, Patia, Bhubaneswar – 751024, Odisha, India

DOI:

https://doi.org/10.3329/bjms.v25i10.86645

Keywords:

Immunohistochemistry, Malignant Melanoma, Melanocytes, Myxoid, Spindle cells

Abstract

Malignant myxoid melanoma histologically presents as atypical spindle cells in a background of dense mucin deposition in connective tissue. It a is a rare variant of malignant melanoma. A substantial overlap in clinical and pathologic features of this variant with other arrays of myxoid containing tumors makes a definitive diagnosis challenging. The myxoid component seen is a response to the tumor cells and therefore is usually seen in metastatic lesions. Though few cases have been reported on skin and face, this case reports the first case of primary myxoid malignant melanoma in the oral cavity. To conclude, proper co-relation of histopathological and immunohistochemical study is the gateway for final diagnosis of myxoid variant of malignant melanoma.

Bangladesh Journal of Medical Science Vol. 25. Supplementary Issue 2026, Page : S180-S183

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Published

2026-01-06

How to Cite

Mishra, P., Bhuyan, L., Sundaragiri, K. S., Dakshinakabat, P., Prasad, H., & Kumar, V. (2026). An unusual variant of primary oral malignant myxoid melanoma with varied clinical significance. Bangladesh Journal of Medical Science, 25(10), S180-S183. https://doi.org/10.3329/bjms.v25i10.86645

Issue

Vol: 25. Supplementary issue 2026

Section

Case Reports

License

Copyright (c) 2026 Pallavi Mishra, Lipsa Bhuyan , Krishna Sireesha Sundaragiri, Prachurya Dakshinakabat, Harikrishnan Prasad, Vijay Kumar

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