Tumor Associated Macrophages-Friends Turned Foe? A Case Report and Review of Literature

Authors

  • Zeeba Shamim Jairajpuri Assistant Professor, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, Hamdard Nagar, New Delhi 110062
  • Usha Agarwal Deputy Director, Institute of Pathology, Indian Council of Medical Research, Safdarjung Hospital Campus, New Delhi

DOI:

https://doi.org/10.3329/bjms.v11i2.8928

Keywords:

Tumor associated macrophages, breast carcinoma, angaiogenesis

Abstract

Most malignant tumors are infiltrated by inflammatory cells and it has long been considered that such infiltrates may be evidence of a host response to the tumor. Although lymphocytes are prominent in the inflammatory infiltrate, macrophages are also present, often in considerable numbers. Breast carcinoma is one such tumor where tumor associated macrophages (TAM) have been reported to be widespread, more so in Western literature. There is paucity of information about the biological and prognostic significance of this phenomenon in India. Ours is a tertiary center which receives approximately100 to120cases of breast carcinoma for pathological evaluation annually. Here we report the first case in our experience which showed large numbers of macrophages infiltrating the stroma around the tumor cells.

DOI: http://dx.doi.org/10.3329/bjms.v11i2.8928

Bangladesh Journal of Medical Science Vol. 11 No. 02 April 2012: 139-142

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Published

2012-07-31

How to Cite

Jairajpuri, Z. S., & Agarwal, U. (2012). Tumor Associated Macrophages-Friends Turned Foe? A Case Report and Review of Literature. Bangladesh Journal of Medical Science, 11(2), 139–142. https://doi.org/10.3329/bjms.v11i2.8928

Issue

Vol. 11 No. 2 (2012)

Section

Case Reports

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