Ancient Neurilemoma of the Lower Lip Mimicking Malignancy: A case report with Histopathologic Challenge

Authors

  • Kailash Chandra Dash Professor, Dept. of Oral & Maxillofacial Pathology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha.
  • Asutosh Das MDS. Reader, Department of Oral & Maxillofacial Surgery, Kalinga Institute of Dental Sciences, KIIT Deemed to be university.
  • Noureen Nahar Senior lecturer, Oral medicine and oral radiology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University
  • Shubhangi Gupta Assistant professor, Department of oral and maxillofacial surgery, I.T.S Dental college, Hospital and research centre, Greater Noida
  • Sreepreeti Champatyray Associate Professor, Department of Oral Pathology & Microbiology, Institute of Dental sciences, SOA Deemed to be University, Bhubaneswar, Odisha.
  • Lipsa Bhuyan Professor, Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Patia, Bhubaneswar-751024

Keywords:

Ancient Neurilemoma, Mimicking Malignancy

Abstract

Neurilemoma, also known as Schwannoma, is a slowgrowing, benign tumor of the nerve sheath that is comparatively rare in the oral cavity. The “Ancient” variant of neurilemomas presents a substantial diagnostic problem, whereas regular neurilemomas exhibit a characteristic biphasic pattern. A 65-year-old woman with a hard, painless lump on his lower lip is the subject of this case report. Significant nuclear atypia and hyperchromasia were found during the initial histopathologic evaluation, which raised the possibility of a spindle cell sarcoma. Nonetheless, a diagnosis of Ancient Neurilemoma was confirmed by the robust S100 positive and lack of mitotic features. This case emphasizes how crucial it is to identify degenerative changes in order to prevent needless, drastic surgery.

Bangladesh Journal of Medical Science Vol. 25. Supplementary Issue-2 (2026), Page : S359-S362

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Published

2026-06-29

How to Cite

Ancient Neurilemoma of the Lower Lip Mimicking Malignancy: A case report with Histopathologic Challenge. (2026). Bangladesh Journal of Medical Science, 25(20), S359-S362. https://banglajol.info/index.php/BJMS/article/view/91279

Issue

Vol: 25. Supplementary issue 2 (2026)

Section

Case Reports

License

Copyright (c) 2026 Kailash Chandra Dash, Asutosh Das, Noureen Nahar, Shubhangi Gupta, Sreepreeti Champatyray, Lipsa Bhuyan

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How to Cite

Ancient Neurilemoma of the Lower Lip Mimicking Malignancy: A case report with Histopathologic Challenge. (2026). Bangladesh Journal of Medical Science, 25(20), S359-S362. https://banglajol.info/index.php/BJMS/article/view/91279