Utility of Split-hand Index in Amyotrophic Lateral Sclerosis
DOI:
https://doi.org/10.3329/bjn.v36i2.87124Keywords:
Amyotrophic lateral sclerosis, Split-hand Index, Compound muscle action potential, Motor unit number index, F wave persistenceAbstract
Amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder, is the most common type of motor neuron disease (MND). Split-hand is considered to be an early and specific clinical sign in ALS where lateral hand (thenar muscles) is more affected than medial hand (hypothenar muscles). Split-hand index (SI) is an electrophysiological measure to see split-hand and its extent which is simple and can be done in basic electrophysiological setting. It can also differentiate ALS from other mimic disorders. It can be used as a diagnostic as well as prognostic marker of ALS so that patient can undergo an early therapeutic trial.
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Copyright (c) 2026 Sujan Saha, Md. Abdullah Al Muzahid Saha, Ashish Chowdhury Saha, Md. Suman Kabir Saha, Uttam Roy Saha, Hasan Zahidur Rahman Saha, SK Mahbub Alam Saha, Md. Rafiqul Islam Saha

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