Radiosynthesis and Quality Control of [18F] PSMA-1007 at the Cyclotron Facility of National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for Diagnosis of Prostate Cancer

Authors

  • Md Jashim Uddin National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Mohammad Anwar Ul Azim Planning & Development Division, Bangladesh Atomic Energy Commission (BAEC).
  • Sanchoy Chandra Biswasarma National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Saiful Islam National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Sanjida Islam National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Mustafa Mamun National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Ferdoushi Begum National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Nahid Hossain National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Shohag Mia National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Hasan Mehdi National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Nur E Alam Siddiquee National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Muhtasin Kadir National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.

DOI:

https://doi.org/10.3329/bjnm.v26i2.71484

Keywords:

(18F) PSMA-1007, prostate cancer, PET imaging, quality control, Bangladesh

Abstract

Radiolabeled tracers targeting prostate-specific membrane antigen (PSMA) have revolutionized PET imaging for prostate cancer diagnosis. Here, we present the inaugural production and quality control assessment of (18F) PSMA-1007 at the National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh. The synthesis, conducted via a one-step procedure, yielded remarkable radiochemical yields (46.85%) with synthesis time 40 minutes. Quality control measures adhered to European Pharmacopoeia standards, enabling clinical deployment across Nuclear Medicine and PET-CT centers in Bangladesh. This pioneering effort marks a significant advancement in prostate cancer imaging within the region.

Bangladesh J. Nuclear Med. 26(2): 198-200, 2023

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Published

2024-06-23

How to Cite

Uddin, M. J., Anwar Ul Azim, M., Biswasarma, S. C., Islam, M. S., Islam, S. ., Mamun, M., … Kadir, M. (2024). Radiosynthesis and Quality Control of [18F] PSMA-1007 at the Cyclotron Facility of National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for Diagnosis of Prostate Cancer . Bangladesh Journal of Nuclear Medicine, 26(2), 198–200. https://doi.org/10.3329/bjnm.v26i2.71484

Issue

Vol. 26 No. 2 (2023)

Section

Short Communication

License

All rights reserved to Editor-in-Chief, Bangladesh Journal of Nuclear Medicine, Society of Nuclear Medicine, Bangladesh