Radiosynthesis and Quality Control of [18F] PSMA-1007 at the Cyclotron Facility of National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for Diagnosis of Prostate Cancer

Authors

  • Md Jashim Uddin National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Mohammad Anwar Ul Azim Planning & Development Division, Bangladesh Atomic Energy Commission (BAEC).
  • Sanchoy Chandra Biswasarma National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Saiful Islam National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Sanjida Islam National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Mustafa Mamun National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Ferdoushi Begum National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Nahid Hossain National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Shohag Mia National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Hasan Mehdi National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Md Nur E Alam Siddiquee National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.
  • Muhtasin Kadir National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh Atomic Energy Commission (BAEC), Block-D, BSMMU campus, Shahbag, Dhaka, Bangladesh.

DOI:

https://doi.org/10.3329/bjnm.v26i2.71484

Keywords:

(18F) PSMA-1007, prostate cancer, PET imaging, quality control, Bangladesh

Abstract

Radiolabeled tracers targeting prostate-specific membrane antigen (PSMA) have revolutionized PET imaging for prostate cancer diagnosis. Here, we present the inaugural production and quality control assessment of (18F) PSMA-1007 at the National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh. The synthesis, conducted via a one-step procedure, yielded remarkable radiochemical yields (46.85%) with synthesis time 40 minutes. Quality control measures adhered to European Pharmacopoeia standards, enabling clinical deployment across Nuclear Medicine and PET-CT centers in Bangladesh. This pioneering effort marks a significant advancement in prostate cancer imaging within the region.

Bangladesh J. Nuclear Med. 26(2): 198-200, 2023

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Published

2024-06-23

How to Cite

Uddin, M. J., Anwar Ul Azim, M., Biswasarma, S. C., Islam, M. S., Islam, S. ., Mamun, M., Begum, F., Hossain, M. N., Mia, M. S., Mehdi, H., Siddiquee, M. N. E. A. ., & Kadir, M. (2024). Radiosynthesis and Quality Control of [18F] PSMA-1007 at the Cyclotron Facility of National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for Diagnosis of Prostate Cancer . Bangladesh Journal of Nuclear Medicine, 26(2), 198–200. https://doi.org/10.3329/bjnm.v26i2.71484

Issue

Vol. 26 No. 2 (2023)

Section

Short Communication

License

All rights reserved to Editor-in-Chief, Bangladesh Journal of Nuclear Medicine, Society of Nuclear Medicine, Bangladesh