TY - JOUR AU - Ul Azim, Mohammad Anwar AU - Islam, Md Ariful AU - Biswasarma, Sanchoy Chandra AU - Uddin, Md Jashim AU - Jabin, Zeenat AU - Begum, Fatima AU - Begum, Shamim MF AU - Alam, Faridul AU - Hasan, Mizanul AU - Nahar, Nurun AU - Haque, Jasmine Ara AU - Rahman, Hosne Ara AU - Hossain, Gazi Abul AU - Rima, Shakila Zaman AU - Nahar, Kamrun AU - Ali, Murshed AU - Das, Jharna AU - Jahan, Nafisa AU - Ahsan, Mostofa Shamim AU - Dey, Shankar Kumar AU - Islam, Md Reajul AU - Awal, Md Abdul AU - Alam, Md Sayeedul AU - Bose, BK AU - Hoque, AHM Roquibul AU - Paul, Ashoke Kumar AU - Nasreen, Faria AU - Hossain, Sanowar AU - Moslem, Fauzia PY - 2022/05/25 Y2 - 2024/03/28 TI - Current Status of Newborn Screening for the early Diagnosis of Congenital Hypothyroidism in Bangladesh JF - Bangladesh Journal of Nuclear Medicine JA - Bangladesh J. Nuclear Med. VL - 25 IS - 1 SE - Original Articles DO - 10.3329/bjnm.v25i1.59636 UR - https://banglajol.info/index.php/BJNM/article/view/59636 SP - 15-21 AB - <p><strong><em>Background: </em></strong>Newborn screening programs signify early and presymptomatic detection of treatable disorders which authorize commencement of prompt medication to alleviate notable fatality. Newborn screening (NBS) for congenital hypothyroidism (CH) has been a successful public health initiative in preventive medicine over the last few decades. Previous pilot (1999-2006) and phase 1 (2006-2011) NBS program in Bangladesh reported an increased incidence compared to global data which urged to initiate a second phase NBS program for the detection of CH.</p><p><strong><em>Materials &amp; Methods: </em></strong>Neonates’ blood was collected from the umbilical cord or by heel prick and drawn on the Guthrie filter paper card. Thyroid-stimulating hormone (TSH) was measured from this filter paper by Immunoradiometric assay (IRMA) or Dissociation Enhanced Lanthanide Fluorescence Immunoassay (DELFIA) method.</p><p><strong><em>Results: </em></strong>123 out of 2,61,550 neonates have already been diagnosed with congenital hypothyroidism from September 2018 to August 2020, which represents an incidence of 1:2126.</p><p><strong><em>Conclusion: </em></strong>Ongoing phase-2 project data is already showing some optimistic outcomes. Hence, a time-worthy sustainable policy should be implemented to mark this program as an effective one.</p><p>Bangladesh J. Nuclear Med. 25(1): 15-21, 2022</p> ER -