Bangladesh Journal of Nuclear Medicine

Abstract of 25th National Conference of Society of Nuclear Medicine, Bangladesh Vol 25(1)

Editor in Chief — 2022-05-25

Abstract not available

Bangladesh J. Nuclear Med. 25(1): 48-67, 2022

Timeless Treasures who Shaped Today’s Glorious Nuclear Medicine of Bangladesh: Interviews with Pioneer Professors

Shamim Momtaz Ferdousi Begum — 2022-05-25

Abstract not available

Bangladesh J. Nuclear Med. 25(1): 11-14, 2022

Performance Evaluation of the Nuclear Medicine Imaging Modalities at NINMAS

Md Nahid Hossain — 2022-05-25

Performance evaluation of the imaging systems of nuclear medicine have been checked and compared with the previous data which were collected at the time of acceptance testing at the National Institute of Nuclear Medicine & Allied Sciences (NINMAS). Performance measurements that have been carried out for the SPECT and SPECT-CT system recently were according to NEMA NU 2-2012 standard and IAEA Human Health Series No.1. Phantoms required for these tests to be performed were supplied by the vendors. Performance tests checked for the SPECT system were intrinsic flood field uniformity, intrinsic spatial resolution, center of rotation (COR), offset and alignment of axes, sensitivity and total performance test. The CT Phantom tests have been carried out for the visual inspection of resolution, contrast, noise and uniformity of the CT system. In these studies, performance evaluations of nuclear medicine imaging modalities including SYMBIA Evo Excel Dual Head SPECT Scanners, SYMBIA T16 SPECT-CT System and Nucline TH-45 Single Head Gamma Camera for Thyroid have been done to ensure the quality of service given to the patients. Performance measurements of these imaging modalities have shown satisfactory image quality. All data were compared with the acceptance testing data which were carried out during installation at the institute.

Bangladesh J. Nuclear Med. 25(1): 28-35, 2022

Current Status of Newborn Screening for the early Diagnosis of Congenital Hypothyroidism in Bangladesh

Mohammad Anwar Ul Azim — 2022-05-25

Background: Newborn screening programs signify early and presymptomatic detection of treatable disorders which authorize commencement of prompt medication to alleviate notable fatality. Newborn screening (NBS) for congenital hypothyroidism (CH) has been a successful public health initiative in preventive medicine over the last few decades. Previous pilot (1999-2006) and phase 1 (2006-2011) NBS program in Bangladesh reported an increased incidence compared to global data which urged to initiate a second phase NBS program for the detection of CH.

Materials & Methods: Neonates’ blood was collected from the umbilical cord or by heel prick and drawn on the Guthrie filter paper card. Thyroid-stimulating hormone (TSH) was measured from this filter paper by Immunoradiometric assay (IRMA) or Dissociation Enhanced Lanthanide Fluorescence Immunoassay (DELFIA) method.

Results: 123 out of 2,61,550 neonates have already been diagnosed with congenital hypothyroidism from September 2018 to August 2020, which represents an incidence of 1:2126.

Conclusion: Ongoing phase-2 project data is already showing some optimistic outcomes. Hence, a time-worthy sustainable policy should be implemented to mark this program as an effective one.

Bangladesh J. Nuclear Med. 25(1): 15-21, 2022

Demography and Characteristics of Lung Cancer Patients Evaluated by 18F-FDG PET- CT imaging - Retrospective Analysis in NINMAS

Abu Bakker Siddique — 2022-05-25

Introduction: Carcinoma of the lung is one of the most common cancer in Bangladesh. Fluorine-18-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) plays an important role in staging and evaluating therapy response. Currently, limited data is available about the demography and characteristics of lung cancer patients in Bangladesh by 18F-FDG PET-CT scan.

Objectives: To evaluate the demographic pattern and pattern of findings in lung cancer patients by 18F-FDG PET-CT scan in the National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Dhaka.

Materials and Methods: This retrospective study was conducted in the PET-CT division of NINMAS. A total of 53 patients out of 103 patients with lung cancer were enrolled who were referred to NINMAS from October 2020 to December 2021 for either baseline PET CT or for assessment of therapy response. Data were collected in a predesigned format from old documents and analyzed for demographic characteristics, histopathologic, morphologic and metabolic patterns as well as a comparison of the overall number of lung cancer patients with previous years.

Results: Among the enrolled 53 lung cancer patients the majority (34%) are in the 6th to 7th decades with 56.6% male and 43.4 % female. Adenocarcinoma (62%) and squamous cell carcinoma (24%) were the most common lung cancer subtypes. The majority of patients (53%) came for a therapeutic response evaluation; among them, 32% had a good response following therapy, 25% with progressive disease and others had mixed response, partial response, and stable disease. Nine percent of the patients came for follow up and among them, recurrence is detected in 20%. Lung cancer patients who came for baseline study, (38%) were upstaged (80%) mainly with 20% remaining in the same stage.

Conclusion: The demographic pattern of lung cancer patients observed in this study belonged to 6th & 7th decades having male predominance. Most of the patients were diagnosed with advanced stages of lung cancer. The use of 18FDG PET-CT is crucial for the staging and diagnosis of suspected lung cancer, as well as therapeutic response and follow-up.

Bangladesh J. Nuclear Med. 25(1): 22-27, 2022

Unusual Recurrence of Malignant Melanoma After 14 Years, diagnosed by 18F-FDG PET-CT Imaging: A Case Report

Papia Akhter — 2022-05-25

According to the World Health Organization, the number of malignant melanoma cases increases faster worldwide. Early diagnosed and adequately managed malignant melanoma shows a good prognosis. Rare cases of late metastasis of melanoma after long disease free survival, and their growing incidences are reported. This reported case is about a metastatic malignant melanoma who was apparently disease free for 14 years but showed late recurrence and earned clinical interest. A 60-year-old male patient was referred to PET-CT division of National Institute of Nuclear Medicine & Allied Sciences (NINMAS) for the evaluation of a biopsy proven malignant melanoma in right inguinal region. The patient presented with a newly developed asymptomatic nodule on his right thigh. Relevant past medical history included a completely excised lesion in his left axilla for malignant melanoma. Fine-needle aspiration and cytological analysis report of new lesion showed subcutaneous localization of malignant melanoma. 18F-FDG PET-CT imaging showed hypermetabolic soft tissue density mass in right inguinal region; Histopathology report (HPR) proved malignant lesion. Multiple hypermetabolic lesions were seen intra abdominally involving spleen and pancreas with corresponding hypodense lesions on CT scan. Multiple hypermetabolic enlarged intraabdominal, right axillary and right inguinal lymph nodes are also evident. After 14 years of disease free survival the reported case developed malignant melanoma with distal metastases. Although late metastasis is uncommon however physicians should be aware of any newly developed suspicious lesions and PET-CT can play an important role in workup for detection of metastases from melanoma.

Bangladesh J. Nuclear Med. 25(1): 45-47, 2022

Primary Idiopathic Congenital Lymphedema Presenting as Swelling of Dorsum of Both Feet – A Case Report

Tanjida Hasan — 2022-05-25

Lymphedema is a debilitating, progressive disease causing major healthcare problem. This condition is broadly classified as primary and secondary lymphedema. Congenital subtype is a rare form of primary lymphedema. Proper history taking and appropriate investigations can rule out the other differentials of lymphedema. Early diagnosis is essential for early treatment which may halt the progression and alleviate symptoms. Lymphoscintigraphy is an important but simple imaging modality which helps to diagnose and grade lymphedema initially as well as in follow up. An interesting case of primary idiopathic congenital lymphedema presenting with dorsum of feet swellings is reported here highlighting the importance of lymphoscintigraphy.

Bangladesh J. Nuclear Med. 25(1): 41-44, 2022

Patient Trend of FDG PET-CT Imaging at NINMAS: Working Experience of First Six Years

Shamim MF Begum — 2022-05-25

Abstract not available

Bangladesh J. Nuclear Med. 25(1): 36-40, 2022