Bangladesh Journal of Pharmacology News | Feature | 12 June 2016
Summary: Milk thistle was found to be effective in the treatment of epilepsy in an animal model study.
Source: Lahore College for Women University
Pakistani scientist Dr. Humaira Majeed Khan and her team conducted an study on pentylenetetrazol-induced mice. Pentylenetetrazol was used to make the epilepsy model and then they have found that milk thistle (Silybum marianum) seed ethanol extract was found to have antiepileptic property. The plant has has been used therapeutically for centuries in the management of liver diseases such as liver cirrhosis, alcoholic hepatitis, liver poisoning, alcoholic fatty liver, and viral hepatitis for centuries. Their data are recently published in Bangladesh Journal of Pharmacology.
Photograph showing the drug-induced seizure in mouse model