Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula Rezt

Authors

  • Mohammad Shoeb Department of Chemistry, University of Dhaka, Dhaka
  • Paul Kong Thoo-Lin School of Pharmacy and Life Science, The Robert Gordon University, Aberdeen
  • Nilufar Nahar Department of Chemistry, University of Dhaka, Dhaka

DOI:

https://doi.org/10.3329/bjp.v7i1.10507

Keywords:

Colon cancer, Cytotoxicity, Endophytic fungus

Abstract

Endophytic microorganisms are fungi or bacteria that live inside the healthy tissues of the host plants causing no apparent symptoms of diseases. Five endophytic fungal strains labeled as IR-1, IR-2, IR-4, IR-6 and IR-7 (identified as Penicillium thiomii) were isolated from the medicinal plant of Terminalia chebula Retz by culture and sub-culture. The ethyl acetate extract of fungal strains, IR-4, IR-6 and IR-7 inhibited the growth of CaCo-2 colon cancer cell lines in MTT assay with IC50 values of 55, 44 and 67 µg/mL, respectively.

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References

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Published

2012-05-09

How to Cite

Shoeb, Mohammad, et al. “Anti-Colon Cancer Activity of Endophytic Fungal Strains from Terminalia Chebula Rezt”. Bangladesh Journal of Pharmacology, vol. 7, no. 1, May 2012, pp. 47-49, doi:10.3329/bjp.v7i1.10507.

Issue

Vol. 7 No. 1 (2012)

Section

Research Articles

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