Effects of Gymnema lactiferum leaves on glycemic and lipidemic status in type 2 diabetes subjects

Authors

  • Thushari Bandara Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura
  • Begum Rokeya Biomedical Research Group, BIRDEM, K. N. Islam Avenue, Dhaka
  • Sakina Khan Biomedical Research Group, BIRDEM, K. N. Islam Avenue, Dhaka
  • Liaquat Ali Biomedical Research Group, BIRDEM, K. N. Islam Avenue, Dhaka
  • Sagarika Ekanayake Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura
  • Errol R. Jansz Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura
  • Kandiah Balasubramanium Biotech (Pvt) Ltd, Jaffna

DOI:

https://doi.org/10.3329/bjp.v4i2.1195

Keywords:

Blood glucose, Cholesterol, Gymnema lactiferum, HbA1C, LDL, Type 2 diabetics

Abstract

Gymnema lactiferum var. lactiferum is a climber distributed in many South Asian countries. It is reported that the diabetic patients in Sri Lanka use G. lactiferum leaves as a treatment for diabetes. However, scientific data is not available on this plant. A clinical trial was conducted including 26, type 2 diabetic patients with hypercholesterolemia. The treatment group received a suspension of G.  lactiferum leaf powder twice daily for  four weeks. Blood parameters of both groups (treated and control) were determined at the beginning and the end of the study period. Study indicates significant effects on fasting blood sugar (p=0.002), cholesterol (p=0.004), and LDL lowering (p=0.023) and a significant postprandial glucose lowering effect (p=0.026 for 60 min and p=0.022 for 120 min, after four weeks). In spite of the short study period, a significant reduction (p=0.012) in HbA1C levels was also observed.

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Published

2009-04-23

How to Cite

Bandara, T., B. Rokeya, S. Khan, L. Ali, S. Ekanayake, E. R. Jansz, and K. Balasubramanium. “Effects of Gymnema Lactiferum Leaves on Glycemic and Lipidemic Status in Type 2 Diabetes Subjects”. Bangladesh Journal of Pharmacology, vol. 4, no. 2, Apr. 2009, pp. 92-95, doi:10.3329/bjp.v4i2.1195.

Issue

Vol. 4 No. 2 (2009)

Section

Research Articles

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