Antimicrobial properties of extracts and compounds isolated from Berberis jaeschkeana
DOI:
https://doi.org/10.3329/bjp.v8i2.13551Keywords:
Alkaloid, Antimicrobial, Columbamine, Zone of inhibitionAbstract
The present study was undertaken to evaluate the anti microbial properties of Berberis jaeschkeana Schneid Var. jaeschkeana for the first time. The screening of B. jaeschkeana for its phytochemical constituents showed the presence of alkaloids, glycosides, flavonoids, steroids, saponins reducing sugars and terpenoids. Crude ethanolic extract and different fractions showed good antimicrobial properties. Five compounds isolated for the first time from this plant also showed good antimicrobial properties. Columbamine was found to have excellent antimicrobial properties among all the compounds.
Downloads
333
182 Read
8
References
Edeoga HO, Okwu DE, Mbaebie BO. Phytochemical constituents of some Nigerian medicinal plants. Afr J Biotechnol. 2005; 4: 685-88.
Hill AF. Economic botany: A textbook of useful plants and plant products. 2nd ed. New York, McGraw-Hill Book Company Inc, 1952.
Jafri SMH. Flora of West Pakistan. Nasir E, Ali SI (eds). Vol. 87. Berberidaceae, 1975, pp 1-36.
Lenka G, Jiri D, Radek M. Quaternary protoberberine alkaloids. Phytochemistry 2007; 68: 150-75.
Mohsen I, Hossein H. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytother Res. 2008; 22: 999-1012.
Radek M, Pavlina S, Dagmar H, Jaromir M, Jiri D, Vladimir S. Palmatine and berberine isolation artifacts. J Nat Prod. 2003; 66: 481-86.
Rashmi A, Rajasekaran, Jagdish P. The genus Berberis Linn.: A Review. Phcog Rev. 2008; 2: 369-85.
Sheng M P, Hsiou Y D, Wen L C, Hang C L. Phenols from the aerial parts of Leonurus sibiricus. Chinese Pharmaceut J. 2006; 58: 35-40.
Tian JH, Yi CC, Yang CW, Chung YC. Chemical constituents from the stems of Mahonia japonica. J Chinese Chem Soc. 2004; 51: 443-46.
Trinh TT, Franke K, Porzel A, Wessjohann L, Tran VS. Quaternary protoberberine alkaloids from Stephania rotunda. J Chem. 2006; 44: 259-64.
Uddin G, Khan AA, Alamzeb M, Ali S, Rashid M, Sadat A, Alam M, Rauf A, Ullah W. Biological screening of ethyl acetate extract of Hedera nepalensis stem. Afr J Pharm Pharmacol. 2012; 6: 2934-37.
Additional Files
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).