Anti-inflammatory activity of bark of Xeromphis spinosa

Authors

  • Biswa Nath Das Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka
  • Achinto Saha Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka
  • Muniruddin Ahmed Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka

DOI:

https://doi.org/10.3329/bjp.v4i1.1630

Keywords:

Anti-inflammatory activity, Carrageenin, Paw edema

Abstract

Thebark of Xeromphis spinosaextracted by a mixture of equal proportions of petroleum ether, ethyl acetate and methanol at an oral dose of 200 and 400 mg/kg body weight exhibited significant anti-inflammatory activity when compared with control.

Downloads

Download data is not yet available.
Abstract
152
Download
187 Read
12

References

Ahmed M, Shikha HA, Shadhu SK, Rahman MT, Datta BK. Analgesic, diuretic and anti-inflammatory principle from Scoparia dulcis. Pharmazie. 2001; 56: 657-60.

Chevallier A. The encyclopedia of medicinal plants. 1st ed. New York, DK Publishing Inc., 1996.

Crunkhorn P, Meacock SC. Mediators of the inflammation induced in the rat paw by carrageenin. Br J Pharmacol. 1971; 42: 392-402.

Ghani A. In: Medicinal plants of Bangladesh with chemical constituents and uses. 2nd ed. Dhaka, Bangladesh, Asiatic society of Bangladesh, 2003, pp 81-82.

Kirtikar KR, Basu BD. Indian medicinal plants. Singh MP, Singh BP. 2nd ed. 1980, p 902.

Kumar V, Abbas AK, Fausto N (eds.) In: Robbins and Cotran pathologic basis of disease. 7th ed. Philadelphia, Elsevier Saunders, 2004, pp 47-86.

Mattison N, Trimple AG, Lasagna I. New drug development in the United States, 1963 through 1984. Clin Pharmacol Ther. 1998; 43: 290-301.

Ronaldo AR, Mariana LV, Sara MT, Adriana BPP, Steve P, Ferreira SH, Fernando QC. Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice. Eur J Pharmacol. 2000; 387: 111-18.

Roy A, Roy SM, Gupta JK, Lahiri SC. A simple device for rapid measurement of rat paw edema for evaluation of anti-inflammatory activity. Indian J Physiol Pharmacol. 1980; 24: 269-72.

Shrotriya S, Ali MS, Saha A, Bachar SC, Islam MS. Anti-inflammatory and analgesic effects of hedychium coronarium koen. Pak J Pharm Sci. 2007; 20: 42-47.

Sosa S, Balicet MJ, Arvigo R, Esposito RG, Pizza C, Altinier GA. Screening of the topical anti-inflammatory activity of some Central American plants. J Ethanopharmacol. 2002; 8: 211-15.

Vinegar R, Schreiber W, Hugo R. Biphasic development of carrageenan edema in rats. J Pharmacol Exp Ther. 1969; 166: 96-103.

Winter CA, Risley EA, Nuss GW. Carrageenin-induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med. 1962; 111: 544-47.

Additional Files

How to Cite

Das, B. N., A. Saha, and M. Ahmed. “Anti-Inflammatory Activity of Bark of Xeromphis Spinosa”. Bangladesh Journal of Pharmacology, vol. 4, no. 1, Aug. 2008, pp. 76-78, doi:10.3329/bjp.v4i1.1630.

Issue

Section

Research Articles