Prescribing trends of statins in Scotland: A drug utilization study

Authors

  • Asadul M. Helali Division of Applied Health Sciences, Institute of Child Health, University of Aberdeen, Scotland
  • James McLay Division of Applied Health Sciences, Institute of Child Health, University of Aberdeen, Scotland
  • Isa Naina Mohamed Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia

DOI:

https://doi.org/10.3329/bjp.v8i4.16772

Keywords:

LDL-C, Incidence, Prevalence, Simvastatin, Statin

Abstract

Statins are highly effective in managing hypercholesterolaemia in patients with or without chronic heart disease due to extensive evidence for safety, efficacy and cost effectiveness. Observational cross sectional retrospective cohort study was done in approximately 200 primary care practices in Scotland. Frequency, rates and time trends for statin prescriptions together with demographic data and the prescribing patterns for high dose simvastatin and newer statins in its place was measured. 63%, 27%, 5%, 4% and 1% patients were prescribed simvastatin, atorvastatin, pravastatin, rosuvastatin and fluvastatin respectively (n=1,91370). Prevalence for individual statin as well as for all statin prescriptions, significantly increased (p<0.05). Except rosuvastatin the incidence of other statins prescription significantly decreased (p<0.05). The highest number of patients, 884 (24%) switched to atorvastatin from high dose simvastatin. Increase in prevalent use and decrease in incident use of statins, implies the diminished cardiovascular disease related mortality and subsequent increased life expectancy of patients with cardiovascular disease.

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Author Biography

Asadul M. Helali, Division of Applied Health Sciences, Institute of Child Health, University of Aberdeen, Scotland

Assistant Professor

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Published

2013-12-09

How to Cite

Helali, A. M., J. McLay, and I. N. Mohamed. “Prescribing Trends of Statins in Scotland: A Drug Utilization Study”. Bangladesh Journal of Pharmacology, vol. 8, no. 4, Dec. 2013, pp. 401-9, doi:10.3329/bjp.v8i4.16772.

Issue

Vol. 8 No. 4 (2013)

Section

Research Articles

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