Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.

Authors

  • Baburao Bhukya Department of Pharmacognosy and Ethnopharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009
  • Rama Narsimha Reddy Anreddy Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009
  • Carey M. William Department of Pharmacognosy and Ethnopharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009
  • Krishna Mohan Gottumukkala Department of Pharmacognosy and Ethnopharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009

DOI:

https://doi.org/10.3329/bjp.v4i2.2112

Keywords:

Analgesic, Anti-inflammatory, Carrageenan, Kydia calycina

Abstract

The methanol extract of leaves of Kydia calycina Roxb. was screened for the analgesic (using hot plate test and acetic acid-induced writhing test in mice) and anti-inflammatory (using rat paw edema test) activity at the doses of 200 and 400 mg/kg body weight. A significant (p<0.0005) analgesic effect was observed with 200 mg/kg and 400 mg/kg in both tests. The maximum anti-inflammatory response was produced at 3 hour with extract doses of 200 and 400 mg/kg. These results suggest that the methanol extract of K. calycina hasexhibited significant analgesic and anti-inflammatory effects, which were comparable with standard drugs.

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Author Biography

Rama Narsimha Reddy Anreddy, Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009

Research Fellow

References

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Published

2009-05-01

How to Cite

Bhukya, B., R. N. R. Anreddy, C. M. William, and K. M. Gottumukkala. “Analgesic and Anti-Inflammatory Activities of Leaf Extract of Kydia Calycina Roxb”. Bangladesh Journal of Pharmacology, vol. 4, no. 2, May 2009, pp. 101-4, doi:10.3329/bjp.v4i2.2112.

Issue

Vol. 4 No. 2 (2009)

Section

Research Articles

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