Antitoxin activity of Mimosa pudica root extracts against Naja naja and Bangarus caerulus venoms

Authors

  • Subramani Meenatchisundaram Department of Microbiology, Nehru Arts and Science College, Coimbatore, India.
  • Selvin Priyagrace Department of Microbiology, Nehru Arts and Science College, Coimbatore, India.
  • Ramasamy Vijayaraghavan Department of Microbiology, Nehru Arts and Science College, Coimbatore, India.
  • Ambikapathi Velmurugan Department of Microbiology, Nehru Arts and Science College, Coimbatore, India.
  • Govindarajan Parameswari Department of Microbiology, PSG College of Arts and Science, Coimbatore
  • Antonysamy Michael Department of Microbiology, PSG College of Arts and Science, Coimbatore, India.

DOI:

https://doi.org/10.3329/bjp.v4i2.2276

Keywords:

Bangarus caerulus, Edema, Mimosa pudica, Naja naja, Venom

Abstract

Aqueous extract of dried roots of Mimosa pudica was tested for inhibitory activity on lethality, phospholipase activity, edema forming activity, fibrinolytic activity and hemorrhagic activity of Naja naja and Bangarus caerulus venoms. The aqueous extract displayed a significant inhibitory effect on the lethality, phospholipase activity, edema forming activity, fibrinolytic activity and hemorrhagic activity. About 0.14 mg and 0.16 mg of M. pudica extracts were able to completely neutralize the lethal activity of 2LD50 of Naja naja and Bangarus caerulus venoms respectively. The present finding suggests that aqueous extract of M. pudica root possesses compounds, which inhibit the activity of Naja naja and Bangarus caerulus venoms.

Downloads

Download data is not yet available.
Abstract
446
Download
208 Read
29

Downloads

Additional Files

Published

2009-05-03

How to Cite

Meenatchisundaram, S., S. Priyagrace, R. Vijayaraghavan, A. Velmurugan, G. Parameswari, and A. Michael. “Antitoxin Activity of Mimosa Pudica Root Extracts Against Naja Naja and Bangarus Caerulus Venoms”. Bangladesh Journal of Pharmacology, vol. 4, no. 2, May 2009, pp. 105-9, doi:10.3329/bjp.v4i2.2276.

Issue

Vol. 4 No. 2 (2009)

Section

Research Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).