Imidazole and its derivatives as potential candidates for drug development

Authors

  • Amara Mumtaz Department of Chemistry, COMSATS Institute of Information Technology Abbottabad
  • Aamer Saeed Department of Chemistry, Quaid-i-Azam University, Islamabad
  • Nighat Fatima Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad
  • Muhammad Dawood Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad
  • Hummera Rafique Department of Chemistry, University of Gujrat, Gujrat
  • Jamshed Iqbal Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad Centre for Drug Development, COMSATS Institute of Information Technology Abbottabad, Abbottabad 22-060

DOI:

https://doi.org/10.3329/bjp.v11i4.26835

Keywords:

Drug development, Imidazole, Review

Abstract

Imidazole and its derivatives are the pharmacological significant scaffolds with the broad spectrum of activities can be synthesized in the laboratory in the single step by the action of the catalyst. The current review summarizes the role of the imidazole and its derivatives during the last decade (2005-2014) for the treatment of many diseases. Review highlights their significant contribution towards the drug development for the treatment of some fatal diseases like HIV, cancer, tuberculosis and hepatitis C. As imidazole and its derivatives continue to play an important role for the treatment of many diseases so there is a need to trigger research in this field.

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Author Biographies

Amara Mumtaz, Department of Chemistry, COMSATS Institute of Information Technology Abbottabad

Assistant Professor

Aamer Saeed, Department of Chemistry, Quaid-i-Azam University, Islamabad

Professor

Google Scholar Citation

Nighat Fatima, Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad

Assistant Professor

Muhammad Dawood, Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad

MS Scholar

Hummera Rafique, Department of Chemistry, University of Gujrat, Gujrat

Assistant Professor

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Published

2016-10-01

How to Cite

Mumtaz, A., A. Saeed, N. Fatima, M. Dawood, H. Rafique, and J. Iqbal. “Imidazole and Its Derivatives As Potential Candidates for Drug Development”. Bangladesh Journal of Pharmacology, vol. 11, no. 4, Oct. 2016, pp. 756-64, doi:10.3329/bjp.v11i4.26835.

Issue

Vol. 11 No. 4 (2016)

Section

Mini Review

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