Effect of Ligustrum lucidum polysaccharide on immunity of immunosuppressed mice

Authors

  • Shi Jing Jing Henan University of Traditional Chinese Medicine, Zhengzhou, Henan 450046
  • Shi Bo Henan University of Traditional Chinese Medicine, Zhengzhou, Henan 450046
  • Miao Mingsan Henan University of Traditional Chinese Medicine, Zhengzhou, Henan 450046
  • Li Qingya

DOI:

https://doi.org/10.3329/bjp.v11iS1.26919

Keywords:

Immunity, Ligustrum lucidum, Mice, Polysaccharide

Abstract

The aim of this study was to observe the effects of Ligustrum lucidum polysaccharide on immune functions of hydrocortisone-induced immuno-suppressed mouse model. There were phagocytic function of mouse perito-neal macrophage, condition of formation of hemolysin and hemolytic plague as well as condition of mouse lymphocyte transformation. The results indicate that through comparison between high-dose, medium-dose, low-dose L. lucidum polysaccharide groups, lentinan group and model group, phagocytic rate and phagocytic index of peritoneal macrophage obviously improved, thus obviously enhancing formation of hemolysin and hemolytic plague, and obviously improving the transformation rate of peripheral blood lymphocyte. Therefore, L. lucidum polysaccharide could markedly improve the immune functions of hydrocortisone-induced immunosuppressed model mouse.

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Published

2016-03-04

How to Cite

Jing, S. J., S. Bo, M. Mingsan, and L. Qingya. “Effect of Ligustrum Lucidum Polysaccharide on Immunity of Immunosuppressed Mice”. Bangladesh Journal of Pharmacology, vol. 11, no. S1, Mar. 2016, pp. S68-S71, doi:10.3329/bjp.v11iS1.26919.

Issue

Vol. 11 (2016): Special Issue

Section

Research Articles

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