Diuretic activity of aqueous extract and smoothie preparation of Verbesina crocata in rat

Authors

  • Anuar Gómez Salazar Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico http://orcid.org/0000-0001-9633-6542
  • Saudy Saret Pérez Pablo Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico http://orcid.org/0000-0001-5745-6437
  • María Mirian Carmona Estévez Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico http://orcid.org/0000-0001-9945-8545
  • María Estela Camargo Meléndez Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico http://orcid.org/0000-0002-6052-0281

DOI:

https://doi.org/10.3329/bjp.v13i3.27584

Keywords:

Diuretic, Verbesina crocata

Abstract

The aim of this study was to evaluate the diuretic activity of aqueous extract of Verbesina crocata at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular filtration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.

Video Clip of Methodology:

Method for diuretic activity: 1 min 37 sec    Click to watch   

Downloads

Download data is not yet available.
Abstract
24
Download
16 Read
4

Author Biographies

Anuar Gómez Salazar, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico

PhD student

Saudy Saret Pérez Pablo, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico

Professor and Head Group researcher

María Mirian Carmona Estévez, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico

Professor and Head Group researcher

María Estela Camargo Meléndez, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 07738, Mexico

Professor and Head Group researcher

Verbesina crocata

Downloads

Additional Files

Published

2018-08-07

How to Cite

Salazar, A. G., S. S. P. Pablo, M. M. C. Estévez, and M. E. C. Meléndez. “Diuretic Activity of Aqueous Extract and Smoothie Preparation of Verbesina Crocata in Rat”. Bangladesh Journal of Pharmacology, vol. 13, no. 3, Aug. 2018, pp. 236-40, doi:10.3329/bjp.v13i3.27584.

Issue

Vol. 13 No. 3 (2018)

Section

Research Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).