Antidiarrheal activity of ethanolic bark extract of <i>Mitragyna diversifolia</i>

Authors

  • - Jebunnessa Department of Botany, University of Chittagong, Chittagong 4331
  • Shaikh Bokhtear Uddin Department of Botany, University of Chittagong, Chittagong 4331
  • M. Mahabub-Uz-Zaman BCSIR Laboratories, Chittagong, Chittagong 4220
  • Rasheda Akter BCSIR Laboratories, Chittagong, Chittagong 4220
  • Nazim Uddin Ahmed BCSIR Laboratories, Chittagong, Chittagong 4220

DOI:

https://doi.org/10.3329/bjp.v4i2.2801

Keywords:

Antidiarrheal activity, Barium sulfate milk, Castor oil, Mitragyna diversifolia

Abstract

The ethanolic bark extract of Mitragyna diversifolia showed significant (p<0.05) antidiarrheal activity on gastrointestinal motility with barium sulfate milk model and castor oil- induced diarrheal model in rats. These result obtained revealed that the bark extract possess pharmacological activity against diarrhea and may possibly explain the use of the plant in traditional medicine.

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Author Biography

- Jebunnessa, Department of Botany, University of Chittagong, Chittagong 4331

Scientific Officer

References

Atta AH, Mouneir SM. Antidiarrheal activity of some Egyptian medicinal plant extracts. J Ethnopharmacol. 2004; 92: 303-09.

Carlos CC, Saniel MC. Etiology and epidemiology of diarrhea. Phillips J Microbio Infect Dis. 1990; 19: 51-53.

Chatterjee TK. Handbook on laboratory mice and rats. 1st ed. Kolkata, Department of Pharmaceutical Technology, Jadavpur University, 1993, p 157.

Gaginella TS, Phillips SF. Ricinoleic acid: Current view of ancient oil. Dig Dis Sci. 1975; 23: 1171-77.

Luderer JR, Dermers IM, Hayes AT. Advances in prostaglandin and thromboxane research. New York, Raven Press, 1980, pp 1633-38.

Mekeon TA, Lin A, Stafford AE. Biosynthesis of ricinoleate in castor oil. Adv Exp Med Biol. 1999, pp. 46437-47.

Ojewole JAO. Evaluation of antidiarrheal, anti-inflammatory and antidiabetic properties of Sclerocarya birrea (A. Rich.) Hochst. stem bark aqueous extract in mice and rats. Phytotherapy Res. 2004; 18: 601-08.

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Published

2009-10-13

How to Cite

Jebunnessa, .-., S. B. Uddin, M. Mahabub-Uz-Zaman, R. Akter, and N. U. Ahmed. “/I>”;. Bangladesh Journal of Pharmacology, vol. 4, no. 2, Oct. 2009, pp. 144-6, doi:10.3329/bjp.v4i2.2801.

Issue

Vol. 4 No. 2 (2009)

Section

Research Articles

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