Increased count of Bacteroides fragilis in the feces of palmar arsenical keratosis patient

Authors

  • Md. Ashraf Ahmad Division of Arsenic Research, Department of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, Dhaka
  • Mir Misbahuddin Division of Arsenic Research, Department of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, Dhaka http://orcid.org/0000-0003-4667-1005
  • Sharmeen Ahmed Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/bjp.v11i3.29255

Keywords:

Bacteroides fragilis, Clinical trial, Feces, Palmar arsenical keratosis

Abstract

Chronic exposure to high concentration of arsenic caused an increase in the colony count of Bacteroides fragilis in the feces in comparison to healthy volunteer (3.6 × 10¹¹ ± 1.9 vs 1.5 × 10¹¹ ± 1.7 CFU/g of feces) which was not statistically significant. But significant increase in the colony count of B. fragilis was seen in the feces of palmar arsenical keratosis patient (4.2 × 10¹¹ ± 1.9 CFU/g of feces; p=0.0390). Supplementation with probiotic for 12 weeks decreased the colony counts in all three groups which were not statistically significant among the groups. Probiotics decreased the amount of arsenic in the nail of all the three groups significantly.

 

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Author Biography

Mir Misbahuddin, Division of Arsenic Research, Department of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, Dhaka

Professor

Cell: 880-1849396067; email: dgdabd@gmail.com

ORCHID ID: 0000-0003-4667-1005

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Additional Files

Published

2016-08-20

How to Cite

Ahmad, M. A., M. Misbahuddin, and S. Ahmed. “Increased Count of Bacteroides Fragilis in the Feces of Palmar Arsenical Keratosis Patient”. Bangladesh Journal of Pharmacology, vol. 11, no. 3, Aug. 2016, pp. 734-40, doi:10.3329/bjp.v11i3.29255.

Issue

Vol. 11 No. 3 (2016)

Section

Clinical Trial

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