Pattern of skin bacteria in palmar arsenical keratosis

Authors

  • Nadia Bintha Khalil Division of Arsenic Research, Department of Pharmacology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Mir Misbahuddin Division of Arsenic Research, Department of Pharmacology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Dhaka http://orcid.org/0000-0003-4667-1005
  • Abu Naser Ibne Sattar Department of Microbiology and Immunology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/bjp.v11i4.30465

Keywords:

Arsenical keratosis, Bacteria, Palm, Skin

Abstract

The aim of the present study was to examine the involvement of skin bacteria in the pathogenesis of keratosis. Skin swab of five different sites (palm, dorsum of the hand, chest, axilla and alar crease) from arsenic unexposed volunteer (n = 15), arsenic exposed (n = 15) and arsenicosis patients (n= 20) were collected for bacterial culture. The skin of arsenic unexposed volunteers contained Staphylococcus epidermidis and Bacillus spp. Chronic exposure to high concentration of arsenic through drinking water altered the skin bacterial pattern. The growth of Pseudomonas spp. increased in different sites of the skin. But in patient of arsenicosis, the skin of the palm shows the growth of Enterobacter spp.

Downloads

Download data is not yet available.
Abstract
10
Download
17 Read
1

Author Biography

Mir Misbahuddin, Division of Arsenic Research, Department of Pharmacology, Faculty of Basic Science and Paraclinical Science, Bangabandhu Sheikh Mujib Medical University, Dhaka

Professor

Cell: 880-1849396067; email: dgdabd@gmail.com

ORCHID ID: 0000-0003-4667-1005

Google Scholar Citation Index

 

References

Aly R, Maibach HI. Aerobic microbial flora of intertrigenous skin. Appl Environ Microbil. 1977; 33: 97-100.

Baker H, Kligman AM. Measurement of transepidermal water loss by electrical hygrometry: Instrumentation and responses to physical and chemical insults. Arch Dermatol. 1967; 96: 441-52.

Bhuiyan HA, Tshering K, Misbahuddin M. Estimation of arsenic in nail using silver diethyldithiocarbamate method. Bangladesh J Pharmacol. 2015; 10: 513-17.

Caussy D. A field guide for detection, management and surveillance of arsenicosis cases. New Delhi, WHO Regional Office for South-East Asia, 2005.

Grice EA, Kong HH, Conlan S, et al. Topographical and temporal diversity of the human skin microbiome. Science 2009; 324: 1190-92.

Grice EZ, Segre JA. The skin microbiome. Nat Rev Microbiol. 2011; 9: 244-53.

Jyoti A, Bonny TS, Hossain MA. Arsenic poisoning alters the composition of skin microbial flora of human. Res J Microbiol. 2011; 6: 524-33.

Kligman AM. The bacteriology of normal skin. In: Skin bacteria and their role. Maibach HI, Hildick-Smith G (ed.). New York, McGraw-Hill, 1965, pp 13-31.

Misbahuddin M. Arsenicosis: A global issue. New York, Science Publishing Group, 2015, pp 1-204.

Downloads

Additional Files

Published

2016-12-16

How to Cite

Khalil, N. B., M. Misbahuddin, and A. N. I. Sattar. “Pattern of Skin Bacteria in Palmar Arsenical Keratosis”. Bangladesh Journal of Pharmacology, vol. 11, no. 4, Dec. 2016, pp. 940-3, doi:10.3329/bjp.v11i4.30465.

Issue

Vol. 11 No. 4 (2016)

Section

Research Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).