In vitro antifungal, anti-oxidant and HPLC analysis of the extracts of Physalis philadelphica

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DOI:

https://doi.org/10.3329/bjp.v12i3.31965

Keywords:

Antifungal, Anti-oxidant, HPLC, Physalis philadelphica

Abstract

The different parts of Physalis philadelphica were evaluated for the antifungal, anti-oxidant and HPLC assay. The methanol extract of leaf showed inhibitory activity against Pencillium digitatum (58% ZI), Aspergillus flavus (95% ZI) and Rhizopus oryzae (96% ZI) at a concentration of 400 ppm. Strong anti-oxidant activities were found in different parts of the plant. The effects of different extraction solvents on the anti-oxidant activity and antifungal activity of the medicinal extracts were observed. The methanol extract from the leaf, stem, fruit and water fractions from the calyx exhibited strong anti-oxidant activity of 94, 89, 88 and 93% respectively. The ethyl acetate extract was found as a best solvent for the recovery of gallic acid in HPLC assay. No correlation was observed between the gallic acid and anti-oxidant capacity of the extracts.

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Published

2017-08-30

How to Cite

Khan, W., J. Bakht, and B. M. Khan. “In Vitro Antifungal, Anti-Oxidant and HPLC Analysis of the Extracts of Physalis Philadelphica”. Bangladesh Journal of Pharmacology, vol. 12, no. 3, Aug. 2017, pp. 313-8, doi:10.3329/bjp.v12i3.31965.

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Research Articles