Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model
DOI:
https://doi.org/10.3329/bjp.v12i4.33240Keywords:
Chronic nonbacterial prostatitis, Cytokines, Prostatitis, Tagetes patula L., Traditional Chinese medicineAbstract
The effectiveness of water decoction of Tagetes patula was studied against the chronic nonbacterial prostatitis in a rat model induced by estradiol subcuta-neously in a castrated male rat. The low-dose decoction of T. patula significantly ameliorated the prostatitis. The low-dose of polysaccharide and supernatant constituent of T. patula decreased the levels of IL-1?, TNF-?, PSA, and EGF, and improved the levels of testosterone and dihydrotestosterone in vivo. Further, the chemical study indicated that flavonoids were predominant in the supernatant constituent of T. patula. The flavonoids and polysaccha-rides were the effective constituents against prostatitis and this effect may be mediated by keeping hormone balance and a down-regulation of the in?ammatory mediator level of the prostate.
Video Clip of Methodology:
9 min 43 Sec Click to watch
Downloads
1
0 Read
1
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
