Is cotoneaster manna improving the treatment of neonatal jaundice?

Authors

  • Moloud Fakhri Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0001-6995-9779
  • Ali Davoodi Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0001-7286-3567
  • Zeinab Hamzegardeshi Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-4150-0576
  • Roya Farhadi Department of Pediatrics, Faculty of Medicine, Bouali Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
  • Nouraldin Mousavinasab Department of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-0631-4233
  • Abbasali Keshtkar Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. http://orcid.org/0000-0002-7305-8639
  • Mohammad Azadbakht Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran./Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran. http://orcid.org/0000-0002-6298-8718

DOI:

https://doi.org/10.3329/bjp.v13i2.36017

Abstract

The aim of this systematic review is to evaluate the effects of cotoneaster manna on neonatal jaundice. The studies were selected from 1980 to 2017 using the main databases. Eight clinical trials with a total of 862 infants were selected from the 116 primary studies. All these trials had at least two groups for which the studied outcomes were measured before the intervention and at 12, 24, 36 and 48 hours after intervention. Generally, the meta-regression analysis showed a direct insignificant relationship between the baseline bilirubin level in the infants before the intervention and the estimated results. Although the findings confirm the effectiveness of cotoneaster manna products in the treatment of neonatal jaundice compared to the standard interventions or treatments (phototherapy), further clinical trials are strongly recommended, especially with larger sample sizes, more extensive geogra-phical areas, and a variety of subjects in different parts of the world.

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Author Biography

Mohammad Azadbakht, Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran./Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Pharmacognosy

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Published

2018-05-31

How to Cite

Fakhri, M., A. Davoodi, Z. Hamzegardeshi, R. Farhadi, N. Mousavinasab, A. Keshtkar, and M. Azadbakht. “Is Cotoneaster Manna Improving the Treatment of Neonatal Jaundice?”. Bangladesh Journal of Pharmacology, vol. 13, no. 2, May 2018, pp. 168-7, doi:10.3329/bjp.v13i2.36017.

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Section

Meta-Analysis